Therapy of acute massive blood loss in a hemophiliac male: case report

Andrey Yul'evich Bulanov; Буланов Андрей Юльевич; Elena Markovna Shulutko; Шулутко Елена Марковна; Evgeniy Evgen'evich Karpov; Карпов Евгений Евгеньевич; Tat'yana Yur'evna Polyanskaya; Полянская Татьяна Юрьевна; Georgiy Vladimirovich Mishin; Мишин Георгий Владимирович; Sergey Aleksandrovich Morozov; Морозов Сергей Александрович; Nikolay Nikolaevich Kalinin; Калинин Николай Николаевич; Aleksandr Vladimirovich Tochenov; Точенов Александр Владимирович; Konstantin Vladimirovich Yatskov; Яцков Константин Владимирович; Vladimir Yur'evich Zorenko; Зоренко Владимир Юрьевич; Magomed Sultanovich Sampiev; Сампиев Магомед Султанович; A Yu Bulanov; Bulanov A Yu; E M Shulutko; Shulutko E M; E E Karpov; Karpov E E; T Yu Polyanskaya; Polyanskaya T Yu; G V Mishin; Mishin G V; S A Morozov; Morozov S A; N N Kalinin; Kalinin N N; A V Tochenov; Tochenov A V; K V Yatskov; Yatskov K V; V Yu Zorenko; Zorenko V Yu; M S Sampiev; Sampiev M S

Therapy of acute massive blood loss in a hemophiliac male: case report

Authors: Bulanov A.Y.¹, Shulutko E.M.¹, Karpov E.E.¹, Polyanskaya T.Y.¹, Mishin G.V.¹, Morozov S.A.¹, Kalinin N.N.¹, Tochenov A.V.¹, Yatskov K.V.¹, Zorenko V.Y.¹, Sampiev M.S.¹, Bulanov AY.², Shulutko EM², Karpov EE², Polyanskaya TY.², Mishin GV², Morozov SA², Kalinin NN², Tochenov AV², Yatskov KV², Zorenko VY.², Sampiev MS²
Affiliations:
2. Hematological Research Center, Moscow
Issue: Vol 83, No 8 (2011)
Pages: 70-73
Section: Editorial
URL: https://ter-arkhiv.ru/0040-3660/article/view/30923
ID: 30923

Cite item

Abstract

A case is reported of management of massive intraoperative blood loss in a male patient with severe hemophilia. Extirpation of hip pseudotumor with one-stage osteosynthesis with an intramedullary joint-pin in a 43 year old male patient was accompanied with 7.5 l blood loss. The infusion-transfusion therapy (ITT) contained transfusion media about 1/3 of the total volume, fresh-frozen plasma and erythrocyte-containing media were used 1:1. Infusion solutions consisted of balanced polyelectrolytic solutions, hydroxyethylated starches 130/0.4, hyperchaes. Intraoperative normovolemic hemodilution and reinfusion of wound blood were made (CellSaver). ITT target markers were standard hemodynamics control tests. Hemostasis monitoring was conducted with thromboelastography. Complex ITT based on modern principles of clinical transfusiology provided a complete and safe compensation of massive intraoperative blood loss in a patient with severe hemophilia.

Keywords

massive blood loss, hemophilia, infusion-transfusion therapy, thromboelastography

References

Kashuk J. L., Moore E. E., Johnson J. L. et al. Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma: packed red blood cells the answer? J. Trauma 2008 65 (2): 261-270.
Duchesne J. C., Hunt J. P., Wahl G. Review of current blood transfusions strategies in a mature level I trauma center: were we wrong for the last 60 years? J. Trauma 2008; 65: 272-276.
Dente C. J., Shaz B. H., Nicholas J. M. et al. Improvements in early mortality and coagulopathy are sustained better in patients with blunt trauma after institution of a massive transfusion protocol in a civilian level I trauma center. J. Trauma 2009; 66: 1616-1624.
Shaz B. H., Dente C. J., Harris R. S. et al. Transfusion management of trauma patients. Anesth. Analg. 2009; 108: 1760- 1768.
Leal S. R., Munoz M., Paramo J. A., Garcia-Erce J. A. Spanish consensus statement on alternatives to allogenic blood transfusion: the "Seville document" Transfusion Alternatives in Transfusion Medicine 2006; 8: 178-202.
Горобец Е. С. Принципы инфузионно-трансфузионной терапии при массивной операционной кровопотере. Соврем. онкол. 2005; 7: 202-208.
Морозов С. А., Петров М. М., Варламова С. В. и др. Алгоритм заготовки компонентов аутокрови у больных гемофилией. В кн.: Материалы научно-практической конференции "Актуальные вопросы гематологии и трансфузиологии". 8 июля 2009 г. Санкт-Петербург: 71-72.
Scheingraber S., Rehm M., Sehmisch C., Finsterer U. Rapid saline infusion produces hyperchloremic acidosis in patients undergoing gynecologic surgery. Anesthesiology 1999; 90: 1265- 1270.
Boldt J., Suttner S., Brosch C. The influence of a balanced volume replacement concept on inflammation, endothelial activation, and kidney integrity in elderly cardiac surgery patients. Intensive Care Med. 2009; 35: 462-470.
Langeron O., Doelberg M., Ang E.-T. et al. Voluven, a lower substituted novel hydroxyethyl starch (HES 130/0,4), causes fewer effects on coagulation in major orthopedic surgery than HES 200/0,5. Anesth. Analg. 2001; 92. 855-862.
Буланов А. Ю., Городецкий В. М., Шулутко Е. М. и др. Влияние различных типов коллоидных объемозамещающих растворов на измененную систему гемостаза. Анестезиол. и реаниматол. 2004; 2: 25-29.
Бутров А. В., Галенко С. В. Комбинированные гипертонические растворы в интенсивной терапии. Новости анестезиол. и реаниматол. 2007; 1: 57-60.
Bundgaard-Nielsen M., Secher N. H., Kehlet H. "Liberal" vs. "restrictive" perioperative fluid therapy - a critical assessment of the evidence. Acta Anaesthesiol. Scand. 2009; 53: 843-851.
Johansson P. I., Ostrowski S. R., Secher N. H. Management of major blood loss: an update. Acta Anaesthesiol. Scand. 2010; 54: 1039-1049.
Щербакова О. В., Буланов А. Ю., Шулутко Е. М. и др. Метод дифференциальной экспресс-диагностики периоперационных кровотечений. Вестн. Рос. ун-та дружбы народов 2005; 31(3): 84-88.

Supplementary files

Supplementary Files

Action

1. JATS XML

Download

Username
Password
Remember me

Forgot password?	Register

Username
Password
Remember me

Forgot password?	Register

Therapy of acute massive blood loss in a hemophiliac male: case report

Full Text

Abstract

Keywords

About the authors

References

Supplementary files

This website uses cookies