The role of thyroid hypofunction in development of metabolic syndrome

Abstract


Aim. To study the role of hypothyroidism and concomitant obesity in the development of metabolic syndrome (MS).
Material and methods. We examined 60 women suffering from obesity and hypothyroidism (TTH 22.24 ± 4.031). We studied lipid spectrum, carbohydrate metabolism, BP and insulin resistance, fat tissue distribution, exercise tolerance.
Results. According to IDF (2005) criteria the women had: metabolic syndrome (83.4%), newly diagnosed hypothyroidism (95%), decompensated hypothyroidism (90%), subclinical hypothyroidism (65%) after six-month replacement therapy with L-T4 MS symptoms declined.
Conclusion. Abnormally high level of TSH may be a component of metabolic syndrome.

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Copyright (c) 2009 Demidova T.Y., Galieva O.R., Demidova T.Y., Galieva O.R.

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