The role of thyroid hypofunction in development of metabolic syndrome


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Aim. To study the role of hypothyroidism and concomitant obesity in the development of metabolic syndrome (MS).
Material and methods. We examined 60 women suffering from obesity and hypothyroidism (TTH 22.24 ± 4.031). We studied lipid spectrum, carbohydrate metabolism, BP and insulin resistance, fat tissue distribution, exercise tolerance.
Results. According to IDF (2005) criteria the women had: metabolic syndrome (83.4%), newly diagnosed hypothyroidism (95%), decompensated hypothyroidism (90%), subclinical hypothyroidism (65%) after six-month replacement therapy with L-T4 MS symptoms declined.
Conclusion. Abnormally high level of TSH may be a component of metabolic syndrome.

参考

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