Synthesis, crystal structure and biological activity of hydroxyphosphonates

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Resumo

A series of О,О-dialkyl((aryl(hydroxy)methyl)phosphonates 1-4 with various substituents at the phosphorus atom was obtained by the Abramov reaction. The structure of the isolated products was confirmed by a complex of physical research methods: NMR, IR spectroscopy, mass spectrometry, and X-ray diffraction analysis. All the obtained compounds demonstrated activity against strains of B. cereus and S. aureus bacteria.

Sobre autores

A. Sedov

Kazan (Volga region) Federal University, Butlerov Institute of Chemistry

Email: sedandrey1998@gmail.com

R. Davletshin

Kazan (Volga region) Federal University, Butlerov Institute of Chemistry

N. Davletshina

Kazan (Volga region) Federal University, Butlerov Institute of Chemistry

Email: kurnosova.nataliya@yandex.ru

K. Ivshin

Kazan (Volga region) Federal University, Butlerov Institute of Chemistry

A. Fedonin

Kazan (Volga region) Federal University, Butlerov Institute of Chemistry

A. Osogostok

Kazan (Volga region) Federal University, Butlerov Institute of Chemistry

M. Shulaeva

Kazan State Medical Academy

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