Synthesis of Functionalized Spiro[1-benzofuran-2,5'-pyrimidine] Derivatives on the Base of 5-Arylidenebarbituric Acids

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Adducts of dimedone and 5-arylidenebarbituric acids react with N-bromosuccinimide in aqueous ethanol to give functionalized spiro[1-benzofuran-2,5'-pyrimidine] derivatives with moderate yields. The interaction of 5-benzylidenebarbituric acid with ethyl acetoacetate in the presence of N-bromosuccinimide leads to spiro[pyrimidine-5,6'-furo[2,3-d]pyrimidine] derivative.

作者简介

A. Andin

FSAEI HE “Far Eastern Federal University”

编辑信件的主要联系方式.
Email: andin.an@dvfu.ru
ORCID iD: 0009-0004-5274-0980
俄罗斯联邦, Universitetskii pr. L, Russky Island, Vladivostok, 690922

M. Engelgardt

FSAEI HE “Far Eastern Federal University”

Email: andin.an@dvfu.ru
俄罗斯联邦, Universitetskii pr. L, Russky Island, Vladivostok, 690922

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