Microcrystalline stress in the pathogenesis of osteoarthritis


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Abstract

Aim. To estimate the rate of articular cartilage microcrystallization in osteoarthritis (OA). Subjects and methods. The investigation included 110 people who had undergone total endoprosthetic replacement for coxarthrosis. A total of 50 patients with total hip endoprosthetic replacement for femoral neck fractures were recruited as a comparison group. An X-ray diffractometer was used to detect crystals. Results. Cartilage mineralization was seen in 72% of the patients with late-stage OA. Conclusion. Articular cartilage microcrystalline stress is a constant sign of late-stage OA requiring further clinical interpretation.

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