Microcrystalline stress in the pathogenesis of osteoarthritis

Abstract


Aim. To estimate the rate of articular cartilage microcrystallization in osteoarthritis (OA). Subjects and methods. The investigation included 110 people who had undergone total endoprosthetic replacement for coxarthrosis. A total of 50 patients with total hip endoprosthetic replacement for femoral neck fractures were recruited as a comparison group. An X-ray diffractometer was used to detect crystals. Results. Cartilage mineralization was seen in 72% of the patients with late-stage OA. Conclusion. Articular cartilage microcrystalline stress is a constant sign of late-stage OA requiring further clinical interpretation.

References

  1. Antonelli MC, Starz TW. Assessing for risk and progression of osteoarthritis: the nurse’s role: understanding pathophysiology, epidemiology, and risk will aid nurses who are seeking to expand their role in management. Orthop Nurs. 2012;31(2):98-102. doi: 10.1097/nor.0b013e31824fcde4.
  2. DiBonaventura. Impact of self-rated osteoarthritis severity in an employed population: Cross-sectional analysis of data from the national health and wellness survey. Health and Quality of Life Outcomes. 2012;10:30. doi:0.1186/1477-7525-10-30.
  3. Sadosky A, Bushmakin A, Cappelleri JC, Lionberger DR. Relationship between patient-reported disease severity in osteoarthritis and self-reported pain, function, and work productivity. Arthritis Res Ther. 2010;12:162. doi: 10.1186/ar3121.
  4. Eckstein F, Cotofana S, Wirth W et al. Greater rates of cartilage loss in painful knees than in pain-free knees after adjustment for radiographic disease stage: data from the osteoarthritis initiative. Arthritis Rheum. 2011;63(8):57-67. doi: 10.1002/art.30414.
  5. Iqbal MN, Haidri FR, Motiani B, Mannan A. Frequency of factors associated with knee osteoarthritis. J Pak Med Assoc. 2011;61(8):6-9.
  6. Adams CS, Horton WEJR. Chondrocyte apoptosis increases with age in the articular cartilage of adult animals. Anat Rec. 1998;250:418-425. doi: 10.1002/(sici)1097-0185(199804)250:4<418::aid-ar4>3.0.co;2-t.
  7. Buckwalter JA, Martin JA, Brown TD. Perspectives on chondrocyte mechanobiology and osteoarthritis. Biorheology. 2006;43:603-609.
  8. Bullough PG Joints. In: Mills SE, ed. Histology for pathologists, 3-rd edn. Lippincott Williams & Wilkins, Philapelphia; 2007. doi: 10.1136/emj.19.2.187-c.
  9. Дубиков А.И. Остеоартроз: старая болезнь, новые подходы. Современная ревматология. 2013;2:83-86. doi: 10.14412/1996-7012-2013-2388.
  10. Dedrick DK, Goldstein SA, Brandt KD et al. A longitudinal study of subchondral plate and trabecular bone in cruciate-deficient dogs with osteoarthritis followed up for 54 months. Arthritis Rheum. 1993;36:60-67. doi: 10.1002/art.1780361019.
  11. Hayami T, Pickarski M, Zhuo Y et al. Characterization of articular cartilage and subchondral bone chang-es in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis. Bone. 2006;38:34-43. doi: 10.1016/j.bone.2005.08.007.
  12. Кабалык М.А., Дубиков А.И., Петрикеева Т.Ю., Карабцов А.А., Кузьмин И.И., Череповский А.В. Феномен микрокристаллического стресса при остеоартрозе. Тихоокеанский медицинский журнал. 2014;1:70-74.
  13. Kabalyk M, Dubikov A, Petrikeeva T, Korabtsov A, Kuzmin I. Phenomenon of cartilage micro-crystallization in hip osteoarthritis and avascular necrosis of the femoral head. Eur J Int Med. 2013;24:117. doi: 10.1016/j.ejim.2013.08.297.
  14. Kabalyk M, Dubikov A. Mycrocrystallic stress phenomenon in osteoarthritis. Int J Rheum Dis. 2014;17:18.
  15. Клинические рекомендации. Ревматология. Под ред. Насонова Е.Л. М.: ГЭОТАР-Медиа; 2011.
  16. Altman R, Alarcon G, Appelrouth D. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum. 1991;34:505-514. doi: 10.1002/art.1780340502.
  17. Kellgren JH, Lawrence JS. Radiological assessment of osteoarthrosis. Ann Rheum Dis. 1957;16(4):494-502.
  18. Harris WH. Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. J Bone Joint Surg Am. 1969; 51(4):37-55.
  19. Bonica JJ. Evolution and current status of pain programs. J Pain Symptom Manage. 1990;5(6):68-74. doi: 10.1016/0885-3924(90)90032-f.
  20. Fuerst M, Bertrand J, Lammers L et al. Calcification of articular cartilage in human osteoarthritis. Arthritis Rheum. 2009;60(9):694-703.
  21. Mitsuyama H, Healey RM, Terkeltaub RA et al. Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis. Osteoarthritis Cartilage. 2007;15(5):59-65. doi: 10.1016/j.joca.2006.10.017.
  22. Typpö T. Osteoarthritis of the hip. Radiologic findings and etiology. Ann Chir Gynaecol. 1985;201(1)Suppl: 38.

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