电邮这篇文章 Changes in orthogonal ECG in hypertensive patients taking different antihypertensive therapy
- 作者: Sakhnova T.A.1, Blinova E.V.1, Ryabykina G.V.1, Shutova L.I.1, Chikhladze N.M.1, Martynyuk T.V.1, Chazova I.E.1, Sakhnova TA2, Blinova EV2, Ryabykina GV2, Shutova LI2, Chikhladze NM2, Martynyuk TV2, Chazova IE2
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隶属关系:
- Research Cardiology Center, Moscow
- 期: 卷 83, 编号 4 (2011)
- 页面: 39-42
- 栏目: Editorial
- ##submission.dateSubmitted##: 10.04.2020
- ##submission.datePublished##: 15.04.2011
- URL: https://ter-arkhiv.ru/0040-3660/article/view/30835
- ID: 30835
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Material and methods. Orthogonal ECG parameters and those of 24-h blood pressure monitoring (BPM) were examined before and after antihypertensive treatment with different drugs in 95 hypertensive patients aged 47±1 years. Of them, 14 patients received trandolapril+verapamil SR for 2 months, 13 patients - candesartan for 3 months, 25 patients - ramipril for 5 months, 26 patients - carvedilol for 4 months, 10 patients - atenolol for 8 months, 7 patients - doxasozine for 5 months.
Results. 24-h BPM parameters improved in all the groups . Initially, conventional ECG evidence on left ventricular hypertrophy was not seen in 86% patients. Dynamics of orthogonal ECG showed that parameters which increase in left ventricular hypertrophy decrease in response to treatment in patients with baseline values above the median. Parameters G and Gx,which in left ventricular hypertrophy diminish, rise significantly in patients with baseline values under median due to therapy. Treatment with impact on renin-angiotensin system reduced voltage parameters of orthogonal ECG, improved G characterizing repolarisation. Treatment with adrenoreceptors blockers reduced IADI.
Conclusion. The analysis of parameters of orthogonal ECG reveals positive dynamics in response to treatment in patients with insignificant changes on ECG in short follow-up. Drugs of different groups change different parameters of orthogonal ECG.
作者简介
Tamara Sakhnova
Email: blinova@psk-net.ru
Elena Blinova
Email: blinova@psk-net.ru
Galina Ryabykina
Email: ecg.newtekh@gmail.com
Lyudmila Shutova
Novella Chikhladze
Email: novella.cardio@mail.ru
Tamara Martynyuk
Irina Chazova
T Sakhnova
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
E Blinova
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
G Ryabykina
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
L Shutova
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
N Chikhladze
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
T Martynyuk
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
I Chazova
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
参考
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- Verdecchia P., Reboldi G., Angeli F. et al. Prognostic value of serial electrocardiographic voltage and repolarization changes in essential hypertension: the HEART survey study. Am. J. Hypertens. 2007; 20: 997-1004.
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