Email this article Changes in orthogonal ECG in hypertensive patients taking different antihypertensive therapy
- Authors: Sakhnova T.A.1, Blinova E.V.1, Ryabykina G.V.1, Shutova L.I.1, Chikhladze N.M.1, Martynyuk T.V.1, Chazova I.E.1, Sakhnova TA2, Blinova EV2, Ryabykina GV2, Shutova LI2, Chikhladze NM2, Martynyuk TV2, Chazova IE2
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Affiliations:
- Research Cardiology Center, Moscow
- Issue: Vol 83, No 4 (2011)
- Pages: 39-42
- Section: Editorial
- URL: https://ter-arkhiv.ru/0040-3660/article/view/30835
- ID: 30835
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Abstract
Material and methods. Orthogonal ECG parameters and those of 24-h blood pressure monitoring (BPM) were examined before and after antihypertensive treatment with different drugs in 95 hypertensive patients aged 47±1 years. Of them, 14 patients received trandolapril+verapamil SR for 2 months, 13 patients - candesartan for 3 months, 25 patients - ramipril for 5 months, 26 patients - carvedilol for 4 months, 10 patients - atenolol for 8 months, 7 patients - doxasozine for 5 months.
Results. 24-h BPM parameters improved in all the groups . Initially, conventional ECG evidence on left ventricular hypertrophy was not seen in 86% patients. Dynamics of orthogonal ECG showed that parameters which increase in left ventricular hypertrophy decrease in response to treatment in patients with baseline values above the median. Parameters G and Gx,which in left ventricular hypertrophy diminish, rise significantly in patients with baseline values under median due to therapy. Treatment with impact on renin-angiotensin system reduced voltage parameters of orthogonal ECG, improved G characterizing repolarisation. Treatment with adrenoreceptors blockers reduced IADI.
Conclusion. The analysis of parameters of orthogonal ECG reveals positive dynamics in response to treatment in patients with insignificant changes on ECG in short follow-up. Drugs of different groups change different parameters of orthogonal ECG.
About the authors
Tamara Anatol'evna Sakhnova
Email: blinova@psk-net.ru
Elena Valentinovna Blinova
Email: blinova@psk-net.ru
Galina Vladimirovna Ryabykina
Email: ecg.newtekh@gmail.com
Lyudmila Ivanovna Shutova
Novella Mikhaylovna Chikhladze
Email: novella.cardio@mail.ru
Tamara Vital'evna Martynyuk
Irina Evgen'evna Chazova
T A Sakhnova
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
E V Blinova
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
G V Ryabykina
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
L I Shutova
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
N M Chikhladze
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
T V Martynyuk
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
I E Chazova
Research Cardiology Center, MoscowResearch Cardiology Center, Moscow
References
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