Physical exercise in combined outpatient rehabilitation of coronary patients with biliary dysfunction
- Authors: Aronov D.M.1, Gulyaeva S.F.1, Shikhova E.V.1, Vedernikov V.A.1, Aronov DM2, Gulyaeva SF3, Shikhova EV3, Vedernikov VA4
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Affiliations:
- State Research Center for Preventive Medicine
- State Medical Academy, Kirov
- Regional Cardiological Center, Kirov
- Issue: Vol 83, No 1 (2011)
- Pages: 21-25
- Section: Editorial
- Submitted: 10.04.2020
- Published: 15.01.2011
- URL: https://ter-arkhiv.ru/0040-3660/article/view/30782
- ID: 30782
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Full Text
Abstract
Material and methods. A two-stage trial was conducted. Stage 1: 237 coronary patients responded to questionnaire detecting incidence of GIS including GBD 8 weeks after ACE. Stage 2: 85 coronary patients with verified GBD were examined for efficacy of rehabilitation. Of them, 43 patients entered PE group while 42 patients entered a control group. The latter received standard therapy without PE. The efficacy of the treatment was evaluated by clinical, device and biochemical findings at baseline and 12 months later.
Results. Of 237 coronary patients 217 (91.7%) patients 2 months after ACE had symptoms of coronary insufficiency, 192 (81.3%) had GIS, 78.9% had GBD. Patients from PE group significantly improved exercise tolerance (bicycle exercise test reached 79.3±15 and 121.3±14.5 bt (p < 0.05), respectively. These patients demonstrated improvement of gall-bladder contraction, a decrease in the level of total cholesterol from 6.12±0.4 to 4.7±0.2 mmol/l (p < 0.05), of LDLP cholesterol from 3.85±0.21 to 2.86±0.32 mmol/l (p < 0.05), thioldisulphide coefficient from 13±0.3 to 2.7±0.4 (p < 0.01). The intergroup analysis 12 months after the study revealed significant differences in favor of the PE group. A weekly number of anginal attacks reduced from 5.1±1.5 to 1.3±1.4 (p < 0.01).
Conclusion. The exercise program is rather effective and can be practiced outpatiently in coronary patients after ACE associated with GBD. It can be also used for secondary prophylaxis of cholestasis in coronary patients with biliary problems.
About the authors
David Meerovich Aronov
Svetlana Fedorovna Gulyaeva
Ekaterina Viktorovna Shikhova
Email: ek_ shikhova @mail.ru
Valeriy Alekseevich Vedernikov
D M Aronov
State Research Center for Preventive MedicineState Research Center for Preventive Medicine
S F Gulyaeva
State Medical Academy, KirovState Medical Academy, Kirov
E V Shikhova
State Medical Academy, KirovState Medical Academy, Kirov
V A Vedernikov
Regional Cardiological Center, KirovRegional Cardiological Center, Kirov
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