Evaluation of the impact of community-acquired pneumonia on short-term and long-term prognosis in a patient with chronic decompensated heart failure

Abstract

Aim. To evaluate the impact of community-acquired pneumonia (CAP) on short-term and long-term prognosis in patients hospitalized with signs of chronic decompensated heart failure (CDHF). Subjects and methods. A total of 852 cases were admitted to therapy/cardiology hospital with signs of CDHF during a year. Results. Among the patients hospitalized with signs of CDHF, the prevalence of CAP was 16.5%. This indicator did not depend on the age of hospitalized patients. Among the multisystem disorders, hypertension, different forms of coronary heart disease, diabetes mellitus, and chronic obstructive pulmonary disease were more common in the patients with CAP. The presence of the latter in a patient with CDHF statistically significantly increased the length of hospital stay (13.1 versus 11.9 days; p = 0.009) and also the probability of rehospitalization during a year (odds ratio (OR) 1.9; p = 0.02). The presence of CAP in a patient with CDHF resulted in an increase in mortality rates (OR 13.5; p < 0.001); moreover, the highest risk of a fatal outcome was noted on day 1 of hospitalization (12.7%). During one-year follow-up, the risk of death in patients hospitalized with CDHF and concomitant pneumonia proved to be higher (OR 4.8; p < 0.001) than in those without pneumonia.

References

  1. Singanayagam A, Singanayagam A, Elder D, Chalmers J. Is community-acquired pneumonia an independent risk factor for cardiovascular disease? Eur Respir J. 2011;39(1):187-196. doi: 10.1183/09031936.00049111
  2. Мареев В.Ю., Агеев Ф.Т., Арутюнов Г.П., Коротеев А.В., Мареев Ю.В.,Овчинников А.Г., Беленков Ю.Н., Васюк Ю.А., Галявич А.С., Гарганеева А.А., Гиляревский С.Р., Глезер М.Г., Козиолова Н.А., Коц Я.И., Лопатин Ю.М., Мартынов А.И., Моисеев В.С., Ревишвили А.Ш., Ситникова М.Ю., Скибицкий В.В., Соколов Е.И., Сторожаков Г.И., Фомин И.В., Чесникова А.И., Шляхто Е.В. Национальные рекомендации ОССН, РКО и РНМОТ по диагностике и лечению ХСН (четвертый пересмотр). Сердечная недостаточность. 2013;7(81).
  3. Чучалин А.Г., Синкопальников А.И., Страчунский Л.С., Козлов Р.С., Рачина С.А., Яковлев С.В. Внебольничная пневмония у взрослых: практические рекомендации по диагностике, лечению и профилактике. Клиническая микробиология и антимикробная химиотерапия. 2006;1:54-86.
  4. Yancy C, Jessup M, Bozkurt B et al. 2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;128(16):1810-1852. doi: 10.1161/cir.0b013e31829e8807
  5. Bottle A, Aylin P, Bell D. Effect of the readmission primary diagnosis and time interval in heart failure patients: analysis of English administrative data. Eur J Heart Fail. 2014;16(8):846-853. doi: 10.1002/ejhf.129
  6. Kwon B, Kim D, Jang S et al. Prognosis of heart failure patients with reduced and preserved ejection fraction and coexistent chronic obstructive pulmonary disease. Eur J Heart Fail. 2010;12(12):1339-1344. doi: 10.1093/eurjhf/hfq157
  7. Арутюнов А.Г., Драгунов Д.О., Арутюнов Г.П., Рылова А.К., Пашкевич Д.Д., Витер К.В. Первое открытое исследование синдрома острой декомпенсации сердечной недостаточности и сопутствующих заболеваний в Российской Федерации. Независимый регистр ОРАКУЛ-РФ. Кардиология. 2015;55(5):12-21. doi: 10.18565/cardio.2015.5.12-21
  8. Corrales-Medina V, Musher D, Wells G, Chirinos J, Chen L, Fine M. Cardiac Complications in Patients With Community-Acquired Pneumonia: Incidence, Timing, Risk Factors, and Association With Short-Term Mortality. Circulation. 2012;125(6):773-781. doi: 10.1161/circulationaha.111.040766
  9. Metlay J. Testing Strategies in the Initial Management of Patients with Community-Acquired Pneumonia. Ann Int Med. 2003;138(2):109. doi: 10.7326/0003-4819-138-2-200301210-00012
  10. Thomsen R, Kasatpibal N, Riis A, Nørgaard M, Sørensen H. The Impact of Pre-existing Heart Failure on Pneumonia Prognosis: Population-based Cohort Study. J Gen Intern Med. 2008;23(9):1407-1413. doi: 10.1007/s11606-008-0672-3
  11. Fonarow G, Abraham W, Albert N et al. Day of Admission and Clinical Outcomes for Patients Hospitalized for Heart Failure: Findings From the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF). Circulation: Heart Fail. 2008;1(1):50-57. doi: 10.1161/circheartfailure.107.748376
  12. Nieminen M, Brutsaert D, Dickstein K et al. EuroHeart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population. Eur Heart J. 2006;27(22):2725-2736. doi: 10.1093/eurheartj/ehl193
  13. Adams K, Fonarow G, Emerman C et al. Characteristics and outcomes of patients hospitalized for heart failure in the United States: Rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J. 2005;149(2):209-216. doi: 10.1016/j.ahj.2004.08.005
  14. Fonarow G. Factors Identified as Precipitating Hospital Admissions for Heart Failure and Clinical OutcomesFindings From OPTIMIZE-HF. Arch Intern Med. 2008;168(8):847. doi: 10.1001/archinte.168.8.847
  15. Tseng H. Pneumococcal Vaccination and Risk of Acute Myocardial Infarction and Stroke in Men. JAMA. 2010;303(17):1699. doi: 10.1001/jama.2010.529
  16. Siriwardena A, Gwini S, Coupland C. Influenza vaccination, pneumococcal vaccination and risk of acute myocardial infarction: matched case-control study. Canadian Med Assoc J. 2010;182(15):1617-1623. doi: 10.1503/cmaj.091891
  17. Horwood F, Macfarlane J. Pneumococcal and influenza vaccination: current situation and future prospects. Thorax. 2002;57(suppl 2):ii24-ii30. doi: 10.1136/thorax.57.suppl_2.ii24
  18. McMurray J, Adamopoulos S, Anker S et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012;33(14):1787-1847. doi: 10.1093/eurheartj/ehs104

Copyright (c) 2016 Polyakov D.S., Fomin I.V., Valikulova F.Y., Vaisberg A.R., Kraiem N.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
 

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Managing Editor:

 

© 2018-2021 "Consilium Medicum" Publishing house


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies