Role of measurement of fractional flow reserve in coronary artery atherosclerosis


Cite item

Full Text

Abstract

The paper considers coronary flow in health and coronary flow autoregulation in health and disease. It gives basic methods used to estimate coronary flow reserve in patients with coronary atherosclerosis. The physiological bases for determining fractional flow reserve are presented. Clinical trials investigating the use of fractional flow reserve in patients with coronary heart disease are analyzed.

References

  1. Заболеваемость взрослого населения России в 2011 году. Статистические материалы, часть III. 2012 г.
  2. ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J. 2014;35(37):2541-2619.
  3. Canty JM Jr, Brooks A. Phasic volumetric coronary venous outflow patterns in conscious dogs. Am J Physiol. 1990;258(5 Pt 2):H1457-1463.
  4. Laughlin MH, Davis MJ, Secher NH, van Lieshout JJ, Arce-Esquivel AA, Simmons GH, Bender SB, Padilla J, Bache RJ, Merkus D, Duncker DJ. Peripheral circulation. Compr Physiol. 2012;2(1):321-447.
  5. Klocke FJ. Coronary blood flow in man. Prog Cardiovasc Dis. 1976;19(2):117-166.
  6. Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald’s heart disease: a textbook of cardiovascular medicine. 10th ed.
  7. Gould KL. Does coronary flow trump coronary anatomy? JACC Cardiovasc Imaging. 2009;2(8):1009-1023.
  8. Johnson NP, Kirkeeide RL, Gould KL. Is discordance of coronary flow reserve and fractional flow reserve due to methodology or clinically relevant coronary pathophysiology? JACC Cardiovasc Imaging. 2012;5(2):193-202.
  9. Kern MJ, Lerman A, Bech JW, De Bruyne B. American Heart Association Committee on Diagnostic and Interventional Cardiac Catheterization, Council on Clinical Cardiology. Physiological assessment of coronary artery disease in the cardiac catheterization laboratory: a scientific statement from the American Heart Association Committee on Diagnostic and Interventional Cardiac Catheterization, Council on Clinical Cardiology. Circulation. 2006;114(12):1321-1341.
  10. Pijls NH, Sels JW. Functional measurement of coronary stenosis. J Am Coll Cardiol. 2012;59(12):1045-1057.
  11. Pijls NH, van Son JA, Kirkeeide RL, De Bruyne B, Gould KL. Experimental basis of determining maximum coronary, myocardial, and collateral blood flow by pressure measurements for assessing functional stenosis severity before and after percutaneous transluminal coronary angioplasty. Circulation. 1993;87(4):1354-1367.
  12. de Bruyne B, Bartunek J, Sys SU, Pijls NH, Heyndrickx GR, Wijns W. Simultaneous coronary pressure and flow velocity measurements in humans. Feasibility, reproducibility, and hemodynamic dependence of coronary flow velocity reserve, hyperemic flow versus pressure slope index, and fractional flow reserve. Circulation. 1996;94(8):1842-1849.
  13. De Bruyne B, Bartunek J, Sys SU, Hendrickx GR. Relation between myocardial fractional flow reserve calculated from coronary pressure measurements and exercise-induced myocardial ischemia. Circulation. 1995;92:39-46.
  14. McGeoch RJ, Oldroyd KG Pharmacological options for inducing mMaximal hyperaemia during studies of coronary physiology. Catheter Cardiovasc Interv. 2008;71:198-204.
  15. Yoon YE, Koo BK. Non-invasive functional assessment using computed tomography: when will they be ready for clinical use? Cardiovasc Diagn Ther. 2012;2(2):106-112.
  16. Rajani R, Wang Y, Uss A, Perera D, Redwood S, Thomas M, Chambers JB, Preston R, Carr-White GS, Liatsis P. Virtual fractional flow reserve by coronary computed tomography — hope or hype? EuroIntervention. 2013;9(2):277-284. doi: 10.4244/eijv9i2a44.
  17. Kholodov AS, Simakov SS. Computational study of oxygen concentration in human blood under low frequency disturbances. Mathematical models and computer simulations. 2009;1(2):283-295.
  18. Vassilevski YV, Simakov SS, Kapranov SA. A multi-model approach to intravenous filter optimization. Int J Numerical Methods Biomed Engineering. 2010;26:915-925.
  19. Dobroserdova T, Olshanskii M. A finite element solver and energy stable coupling for 3D and 1D fluid models. Computer Methods in Applied Mechanics and Engineering. 2013;259:166-176.
  20. Gamilov T, Ivanov Yu, Kopylov P, Simakov S, Vassilevski Yu. Patient specific haemodynamic modeling after occlusion treatment in leg. Mathematical Modelling of Natural Phenomena. 2014;9(6):85-97.
  21. Pijls NH, van Schaardenburgh P, Manoharan G, Boersma E, Bech JW, van’t Veer M, Bär F, Hoorntje J, Koolen J, Wijns W, de Bruyne B. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER Study. J Am Coll Cardiol. 2007;49(21):2105-2111.
  22. Tonino PA, De Bruyne B, Pijls NH; FAME Study Investigators. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009;360(3):213-224.
  23. Pijls NH, Fearon WF, Tonino PA; FAME Study Investigators. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention in patients with multivessel coronary artery disease: 2-year follow-up of the FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) study. J Am Coll Cardiol. 2010;56(3):177-184.
  24. De Bruyne B, Pijls NH, Kalesan B; FAME 2 Trial Investigators. Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease. N Engl J Med. 2012;367(11):991-1001.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2015 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
 

Address of the Editorial Office:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Correspondence address:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Managing Editor:

  • Tel.: +7 (926) 905-41-26
  • E-mail: e.gorbacheva@ter-arkhiv.ru

 

© 2018-2021 "Consilium Medicum" Publishing house


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies