Terapevticheskii arkhivTerapevticheskii arkhivТерапевтический архив0040-36602309-5342LLC Obyedinennaya Redaktsiya31840Editorial articleПередовая статьяReview ArticleRole of measurement of fractional flow reserve in coronary artery atherosclerosisРоль измерения фракционированного резерва кровотока при атеросклерозе коронарных артерийKopylovF YuКопыловФ ЮBykovaA AБыковаА АVasilevskyYu VВасилевскийЮ ВSimakovS SСимаковС С«Первый МГМУ им. И.М. Сеченова» Минздрава России«Институт вычислительной математики» РАН«Московский физико-технический институт»«Институт вычислительной математики» РАН«Московский физико-технический институт»«Институт автоматизации проектирования» РАН, Москва15092015879VOL 87, NO9 ()ТОМ 87, №9 (2015)10611310042020Copyright ©; 2015, Consilium MedicumCopyright ©; 2015, ООО "Консилиум Медикум"2015Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://ter-arkhiv.ru/0040-3660/article/view/31840

The paper considers coronary flow in health and coronary flow autoregulation in health and disease. It gives basic methods used to estimate coronary flow reserve in patients with coronary atherosclerosis. The physiological bases for determining fractional flow reserve are presented. Clinical trials investigating the use of fractional flow reserve in patients with coronary heart disease are analyzed.

В статье рассмотрено коронарное кровообращение в условиях нормы, авторегуляция коронарного кровотока в норме и патологии. Приведены основные методы, используемые для оценки резерва коронарного кровотока у пациентов с коронарным атеросклерозом. Изложены физиологические основы определения фракционированного резерва кровотока. Проведен анализ клинических исследований, изучавших использование фракционированного резерва кровотока, у пациентов с ишемической болезнью сердца.

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