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Clinicopathogenetic variants of anemia in patients with intestinal inflammation
- Authors: Drozdov V.N.1, Lishchinskaya A.A.1, Parfenov A.I.1, Noskova K.K.1, Ruchkina I.N.1, Varvanina G.G.1, Tkachenko E.V.1, Drozdov VN2, Lischinskaya AA2, Parfenov AI2, Noskova KK2, Ruchkina IN2, Varvanina GG2, Tkachenko EV2
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Affiliations:
- Central Research Institute of Gastroenterology, Moscow
- Issue: Vol 84, No 2 (2012)
- Pages: 36-41
- Section: Editorial
- URL: https://ter-arkhiv.ru/0040-3660/article/view/30988
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Abstract
Material and methods. A total of 80 patients (56% males and 44% females, mean age 39±15.8 years) with UC and CD were divided into two groups: group 1 - 40 patients with anemia; group 2 - 40 controls free of anemia with the same gender characteristics. The examination protocol included: total blood count, parameters of iron metabolism ( TIBC, LIBC, transferrin saturation with iron, ferritin, transferring, etc.), the levels of erythropoietin, C-reactive protein, TNF-alpha, hepsidin, vitamin B12, folic acid.
Results. Group 1 patients had a significantly lower mean level of iron in the blood and transferrin saturation with iron while the other parameters of iron metabolism (TIBC, LIBC, transferrin, ferritin) did not significantly differ from these of group 2.
Conclusion. Anemia in intestinal inflammation is an independent disease with complicated pathogenesis. This demands complete examination of such patients to prescribe adequate combined treatment of anemia with consideration of all pathogenetic factors of its development.
About the authors
Vladimir Nikolaevich Drozdov
Al'bina Aleksandrovna Lishchinskaya
Email: lalbina@inbox.ru
Asfol'd Ivanovich Parfenov
Email: asfold@mail.ru
Karina Kadievna Noskova
Irina Nikolaevna Ruchkina
Galina Grigor'evna Varvanina
Elena Viktorovna Tkachenko
V N Drozdov
Central Research Institute of Gastroenterology, MoscowCentral Research Institute of Gastroenterology, Moscow
A A Lischinskaya
Central Research Institute of Gastroenterology, MoscowCentral Research Institute of Gastroenterology, Moscow
A I Parfenov
Central Research Institute of Gastroenterology, MoscowCentral Research Institute of Gastroenterology, Moscow
K K Noskova
Central Research Institute of Gastroenterology, MoscowCentral Research Institute of Gastroenterology, Moscow
I N Ruchkina
Central Research Institute of Gastroenterology, MoscowCentral Research Institute of Gastroenterology, Moscow
G G Varvanina
Central Research Institute of Gastroenterology, MoscowCentral Research Institute of Gastroenterology, Moscow
E V Tkachenko
Central Research Institute of Gastroenterology, MoscowCentral Research Institute of Gastroenterology, Moscow
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