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Coronary artery necroses and calcification in chronic coronary heart disease
- Authors: Zhdanov V.S.1, Cherpachenko N.M.1, Drobkova I.P.1, Veselova S.P.1, Shlychkova T.P.1, Zhdanov VS2, Cherpachenko NM2, Drobkova IP2, Veselova SP2, Shlychkova TP2
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Affiliations:
- A. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies
- Issue: Vol 82, No 12 (2010)
- Pages: 16-18
- Section: Editorial
- URL: https://ter-arkhiv.ru/0040-3660/article/view/30718
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Abstract
Subjects and methods. Endarterectomized coronary artery (CA) segments obtained during aortocoronary bypass surgery were pathomorphologically studied in 150 patients aged 49-72 years with coronary heart disease (CHD). CAC was found in 92% of cases. Two types of CAC were identified: one of them was associated with calcified atheromatous masses of atherosclerotic plaques; the other was related to necroses in the fibrous plaque parts. The atheromatous masses exhibited calcareous deposits as fine-grained masses of small extent. In chronic CHD, morphological signs of instability of atherosclerotic plaques were observed in 23.3% of cases, these being associated with lamellar CAC in two thirds.
Conclusion. Calcification in the necrotic area of fibrous parts of stenotic plaques is typical of chronic CHD and is frequently attended by the development of large-focal calcareous deposits generally as laminas (lamellar calcification). Impaired transmural perfusion of plasma is noted to be involved in the development of necroses in stenotic CA atherosclerotic plaques.
About the authors
Valentin Sergeevich Zhdanov
Email: vs.zhdanov@cardio.ru
Nina Mikhaylovna Cherpachenko
Iraida Petrovna Drobkova
Svetlana Petrovna Veselova
Tat'yana Petrovna Shlychkova
V S Zhdanov
A. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical TechnologiesA. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies
N M Cherpachenko
A. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical TechnologiesA. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies
I P Drobkova
A. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical TechnologiesA. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies
S P Veselova
A. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical TechnologiesA. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies
T P Shlychkova
A. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical TechnologiesA. L. Myasnikov Cardiology Research Institute, Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies
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