Patient non-compliance in rheumatoid arthritis: the degree, frequency, types and correlations

Cite item

Full Text


Aim. To assess the degree of non-compliance (NC) in patients with rheumatoid arthritis (RA) as well as N С frequency, types, correlations.
Material and methods. 34 patients with RA (the study group) and 21 patients with osteoarthrosis (the control group) have filled in an original questionnaire developed by the authors. The analysis was made of correlations between N С degree and clinico-laboratory, social-demographic and psychopath-
ological factors.
Results. The degree of NC (general and type-specific) and its frequency appeared to be significantly
higher in the group of RA patients. Significant positive correlations were found between the degree of
NC and hormone dependence, functional decline of the joint, presence of organic and adaptation
mental disorders.
Conclusion. A high degree of RA patient NC with medical recommendations dictates the necessity of
psychocorrective measures for such patients.

About the authors

O V Kremleva

G B Kolotova


  1. Кабанов М. М. Охрана психического здоровья и проблемы стигматизации и комплайенса. Соц. и клин, психиатр. 1998; 2: 58-62.
  2. Bernstein G. A. Imipramine compliance in adolescents. J. Am. Acad. Child Adolesc. Psychiatry 2000; 39 (3): 284-291.
  3. Haynes R. В. Introduction. In: Haynes R. В., Taylor D. W., Sackett D. L., eds. Compliance in health care. Baltimore: Johns Hopkins University Press; 1979. 1-2.
  4. Cramer J. A. Partial medication compliance: the enigma in poor medical outcomes. Am. J. Manag. Care 1995; 1: 45-52.
  5. Haynes R. В., Taylor D. W., Sackett D. L., eds. Compliance in health care. Baltimore: John Hopkins University.Press; 1979.
  6. Lasanga L., ed. Patient compliance. Mount Kisco (NY): Future; 1976.
  7. Sackett D. L., Haynes R. В., Gibson E. S. et al. Randomised clinical trial of strategies for improving medication compliance in primary hypertension. Lancet 1975; 1(7918): 1205 - 1207.
  8. Kirchner J. T. Patient compliance in filling new prescriptions. (Brief article). Am. Fam. Physician 2000; 1.
  9. Meyer U. A., Peck С. С. eds. The drug holiday pattern of noncompliance in clinical trials: Challenge to conventional concepts of drug safety and efficacy. Washington DC: Center for Drug Development Science, Georgetown University; 1997.
  10. Sadovsky R. Optimization of medication use in the elderlypopulation. (Tips from other journals). Am. Fam. Physician 1998; July: 98-103.
  11. Epstein S. Role of behavior theory in behavioral medicine. J. Consult. Clin. Psychol. 1992; 60 (4): 493-498.
  12. McCarthy R. The price you pay for the drug not taken. Business & Health 1998; (16): 27-30.
  13. Urquhart J. When outpatient drug treatment fails: identifying noncompliers as a cost-containment tool. Clin. Res. Reg. Affairs 1994; II: 19-38.
  14. Hunt G. J. Social and cultural aspects of health, illness and treatment. In.: Goldman H. H., ed. Review of general psychiatry. 3th ed. A lange medical book; 1992; s. I., ch. 7: 83-91.
  15. Вассерман Л. И., Вукс А. Я., Иовлев В. В., Карпова Э. Б. Методика для психологической диагностики типов отношения к болезни: Метод, рекомендации. Л.; 1987.
  16. Wood Н. Е., Eeinstein A. R., Taranta A. et al. Rheumatic fever in children and adolescents: a long-term epidemiologic study of subsequent prophylaxis streptococcal infections, and clinical sequelae. III. Comparative effectiveness of three prophylaxis regimens in preventing streptococcal infections and rheumatic recurrences. Ann. Inrern. Med. 1964; 60 (suppl. 5): 31 - 46.
  17. Stenstron C. H., Arge В., Sundbom A. Home exercise and compliance in inflammatory rheumatic diseases - a prospective clinical trial. J. Rheumatol. 1997; 24 (3): 470-476.
  18. Dunbar-Jacob J., Sereika S., Rohay J., Burke L. E. Methods in ambulatory monitoring: assessing adherence to medical regimens. In: Perspectives in behavioral medicine, technological & methodological innovations in behavioral medicine. HillsdalePublisher L. Erlbatun; 1997.

Copyright (c) 2003 Kremleva O.V., Kolotova G.B.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Managing Editor:

  • Tel.: +7 (926) 905-41-26
  • E-mail:


© 2018-2021 "Consilium Medicum" Publishing house

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies