Endobronchial Tuberculosis in an HIV-positive Case
- Authors: Gegin S.1, Özdemir B.1, Günal Ö.2, Topal Ş.2, Uzun Ç.3, Özdemir L.1
-
Affiliations:
- Department of Pulmonology, Samsun Training and Research Hospital
- Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Samsun University
- Department of Pathology,, Samsun Training and Research Hospital
- Issue: Vol 22, No 1 (2024)
- Pages: 1-5
- Section: Medicine
- URL: https://ter-arkhiv.ru/1570-162X/article/view/645320
- DOI: https://doi.org/10.2174/011570162X262663231214053029
- ID: 645320
Cite item
Full Text
Abstract
Introduction:Tuberculosis is an opportunist infection that is fatal and most frequently seen in HIV-positive patients due to immunosuppression. Endobronchial lesions can portray symptoms in different ways. Endobronchial Tuberculosis is one of these lesions.
Case Report:An HIV-positive, untreated 26-year-old patient with fever, cough, and dyspnea consulted our clinic. In the chest X-ray taken, effusion on the right side and non-homogeneous density increase in the middle and upper lobes, bilaterally more prominent on the right side, were observed. Therefore, the patient underwent bronchoscopy because the CT (computerized tomography) showed mediastinal lymphadenopathy (LAP) and an endobronchial lesion in the left main bronchus. During bronchoscopy, a vegetative endobronchial lesion that causes obstruction in the left main bronchus was monitored. With the help of Pathology and PCR results, endobronchial tuberculosis was diagnosed.
Conclusion:Even if Acid-alcohol-resistant Bacillus (ARB) is detected negative in patients who stop responding to antimicrobial treatment and are being monitored under radiological scanning, a distinctive diagnosis of endobronchial tuberculosis should be kept in mind while performing bronchoscopy.
About the authors
Savaş Gegin
Department of Pulmonology, Samsun Training and Research Hospital
Author for correspondence.
Email: info@benthamscience.net
Burcu Özdemir
Department of Pulmonology, Samsun Training and Research Hospital
Email: info@benthamscience.net
Özgür Günal
Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Samsun University
Email: info@benthamscience.net
Şeyma Topal
Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Samsun University
Email: info@benthamscience.net
Çiğdem Uzun
Department of Pathology,, Samsun Training and Research Hospital
Email: info@benthamscience.net
Levent Özdemir
Department of Pulmonology, Samsun Training and Research Hospital
Email: info@benthamscience.net
References
- Judson MA, Sahn SA. Endobronchial lesions in HIV-infected individuals. Chest 1994; 105(5): 1314-23. doi: 10.1378/chest.105.5.1314 PMID: 8181313
- TB profile Available from: https://worldhealthorg.shinyapps.io/tb_profiles/?_inputs_&lan=%22EN%22&entity_type=%22group%22&group_code=%22WPR%22 cited 2023 Apr 16.
- Horner PJ, Moss FM. Tuberculosis in HIV infection. Int J STD AIDS 1991; 2(3): 162-7. doi: 10.1177/095646249100200302 PMID: 1863645
- Hamm PG, Judson MA, Aranda CP. Diagnosis of pulmonary Kaposis sarcoma with fiberoptic bronchoscopy and endobronchial biopsy. A report of five cases. Cancer 1987; 59(4): 807-10. doi: 10.1002/1097-0142(19870215)59:43.0.CO;2-E PMID: 3802039
- Kennedy DJ, Lewis WP, Barnes PF. Yield of bronchoscopy for the diagnosis of tuberculosis in patients with human immunodeficiency virus infection. Chest 1992; 102(4): 1040-4. doi: 10.1378/chest.102.4.1040 PMID: 1395740
- Calpe JL, Chiner E, Larramendi CH. Endobronchial tuberculosis in HIV-infected patients. AIDS 1995; 9(10): 1159-64. doi: 10.1097/00002030-199510000-00007 PMID: 8519452
- Wasser LS, Shaw GW, Talavera W. Endobronchial tuberculosis in the acquired immunodeficiency syndrome. Chest 1988; 94(6): 1240-4. doi: 10.1378/chest.94.6.1240 PMID: 3191766
- Saadoun R, Zoguéreh DD, Niang M, Moreau J. Tuberculose endobronchique se présentant comme une tumeur obstructive chez une patiente VIH-1 positive. Á propos dun cas et revue de la littérature. Rev Med Interne 1998; 19(5): 344-7. doi: 10.1016/S0248-8663(98)80106-9 PMID: 9775170
- Maguire GP, Delorenzo LJ, Brown RB, Davidian MM. Endobronchial tuberculosis simulating bronchogenic carcinoma in a patient with the acquired immunodeficiency syndrome. Am J Med Sci 1987; 294(1): 42-4. doi: 10.1097/00000441-198707000-00006 PMID: 3605189
- Meintjes G, Brust JCM, Nuttall J, Maartens G. Management of active tuberculosis in adults with HIV Lancet HIV 2019; 6(7): e463-74. doi: 10.1016/S2352-3018(19)30154-7
Supplementary files
