Myonecrosis in injection drug users (a clinical case)


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Abstract

Myonecrosis remains one of the severest manifestations of skin and soft tissue infections. Clostridia (C. perfringens, C. novyi, C. septicum, C. sordellii, C. histolyticum) are dominant and Staphylococcus aureus, Streptococcus pyogenes, Bacillus cereus, and Bacteriodes fragilis are much less in the etiology of myonecrosis. Cases of gas gangrene have recently become more frequent among injection drug users all over the world. Russia has become the largest opiate market in Europe and consumption of these narcotic drugs is annually growing. In the Russian Federation, a larger number of injection drug users uniquely results in a rise of cases of Clostridium- and mixed flora-induced myonecrosis. Gas gangrene in HIV-positive drug abusers seems to rapidly progress to multiple organ failure and to show high death rates, rather than to develop a localized form. The analyzed case of mixed flora-induced gas gangrene is of interest to physicians of any specialties who can encounter this wound infection in HIV-positive patients.

About the authors

Irina Viktorovna Shestakova

Email: shes.irin@mtu-net.ru

Nikolay Dmitrievich Yushchuk

Oleg Aleksandrovich Tishkevich

Email: shes.irin@mtu-net.ru

I V Shestakova

Moscow State University of Medicine and Dentistry

Moscow State University of Medicine and Dentistry

N D Yushchuk

Moscow State University of Medicine and Dentistry

Moscow State University of Medicine and Dentistry

O L Tishkevich

Infectious Diseases Hospital Two

Infectious Diseases Hospital Two

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