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Pancreatic cancer risk: alcoholic and non-alcoholic beverages

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1. Title Title of document Pancreatic cancer risk: alcoholic and non-alcoholic beverages
2. Creator Author's name, affiliation, country Irina N. Grigor’eva; Institute of Internal and Preventive Medicine – branch of the Institute of Cytology and Genetics; Russian Federation
3. Subject Discipline(s)
3. Subject Keyword(s) pancreatic cancer; meta-analysis; risk; alcohol; coffee; tea; dairy products
4. Description Abstract

This article provides an overview of the metaanalyzes (PubMed, 1995–2019) of alcohol and non-alcoholic (coffee, tea, dairy products) beverage consumption in relation to risk of pancreatic cancer – PC (PubMed, 1995–2019). Increased the PC risk was associated with high alcohol intake. The increased risk for heavy drinking did not explained by residual confounding by history of pancreatitis or tobacco smoking or diabetes. Light-moderate alcohol intake may reduced the PC risk, probably due to the fasting insulin levels decrement, which leads to the diminished the РС risk. The association between alcohol and the PC was stronger in men than in women. Some metaanalyzes demonstrated that a small amount of coffee may reduce PC risk, and a large amount – to increase PC risk. Another meta-analyzes have not confirmed any association between the PC risk and coffee or tea consumption. One meta-analysis revealed a direct association of the PC risk with the dairy products consumption, but most research showed no such connection. Nutrition is considered to be associated with the PC risk, but the degree of risk due to structure of beverages consumption (dose, duration, alcohol, coffee, tea, dairy products pattern) is still not clear.

5. Publisher Organizing agency, location LLC Obyedinennaya Redaktsiya
6. Contributor Sponsor(s) The work was carried out according to the State task within the framework of the budget topic No. АААА-А17-117112850280-2.
7. Date (DD-MM-YYYY) 15.02.2022
8. Type Status & genre Peer-reviewed Article
8. Type Type Review Article
9. Format File format
10. Identifier Uniform Resource Identifier https://ter-arkhiv.ru/0040-3660/article/view/105595
10. Identifier Digital Object Identifier (DOI) 10.26442/00403660.2022.02.201375
11. Source Title; vol., no. (year) Terapevticheskii arkhiv; Vol 94, No 2 (2022)
12. Language English=en ru
13. Relation Supp. Files
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
15. Rights Copyright and permissions Copyright (c) 2022 Consilium Medicum
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