A case of granulomatous tubulointerstitial nephritis in a patient with pulmonary sarcoidosis

Cover Page


A clinical observation is presented of a patient with pulmonary sarcoidosis, who was diagnosed with kidney damage after three years with the development of chronic renal failure and the need for replacement therapy. A histological examination of the renal biopsy revealed a granulomatous process in the interstitial tissue, which was regarded as an extrapulmonary manifestation of sarcoidosis. Pulse therapy with glucocorticoids was prescribed and an attempt was made to reduce hemodialysis sessions.

Full Text

Restricted Access

About the authors

Leonid I. Dvoretsky

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: dvoretski@mail.ru
ORCID iD: 0000-0003-3186-0102

Russian Federation, Moscow

д.м.н., проф., зав. каф. госпитальной терапии №2

Sergei A. Krivushkin

Yudin City Clinical Hospital

Email: dvoretski@mail.ru
ORCID iD: 0000-0003-0294-6257

Russian Federation, Moscow

зав. нефрологическим отд-нием

Ekaterina S. Stolyarevich

City Clinical Hospital №52

Email: dvoretski@mail.ru
ORCID iD: 0000-0002-0402-8348

Russian Federation, Moscow

врач патологоанатомического отд-ния

Elizaveta A. Skrynnikova

Sechenov First Moscow State Medical University (Sechenov University)

Email: dvoretski@mail.ru
ORCID iD: 0000-0002-9039-1070

Russian Federation, Moscow

студентка 6-го курса

Andrey P. Stepanchenko

Yudin City Clinical Hospital

Email: dvoretski@mail.ru
ORCID iD: 0000-0001-5655-2929

Russian Federation, Moscow

 к.м.н., зав. рентгенологическим отд-нием

Svetlana E. Kolendo

Sechenov First Moscow State Medical University (Sechenov University)

Email: dvoretski@mail.ru
ORCID iD: 0000-0002-1368-1605

Russian Federation, Moscow

доц. каф. госпитальной терапии №2


  1. FGBI «Institute of Pulmonology», et al. DiagnosIs and treatment of sarcoIdosis. summary of federal concilIative clinical recommendations. Part I. classification, etiopathogenesis, clinic. Bull. Contemp. Clin Med. 2014;7:62-70. doi: 10.20969/VSKM.2014.7(4).62-70
  2. Berliner A, Haas M, Choi J. Sarcoidosis: The Nephrologist’s Perspective. Am J Kidney Dis. 2006;48:856-70. doi: 10.1053/ j.ajkd.2006.07.022
  3. Bergner R, Löffler C. Renal sarcoidosis: approach to diagnosis and management. Curr Opin Pulm Med. 2018;24:513-20. doi: 10.1097/MCP.0000000000000504
  4. Naderi S, Amann K, Janssen U. Renal involvement in sarcoidosis: Histologic findings and clinical course. Nephrol. Point Care. 2019;5:1-7. doi: 10.1177/2059300719834928
  5. Stehlé T, Joly D, Vanhille Ph, et al. Clinicopathological study of glomerular diseases associated with sarcoidosis: a multicenter study. Orphan J Rare Dis. 2013;8(65):2-10. doi: 10.1186/1750-1172-8-65
  6. Robson M, Banerjee D, Hopster D, Cairns H. Seven cases of granulomatous interstitial nephritis in the absence of extrarenal sarcoid. Nephrol Dialys Transplant. 2003;18(2):280-4. doi: 10.1093/ndt/18.2.280
  7. Mahévas M, Lescure F, Boffa J, et al. Renal Sarcoidosis: Clinical, Laboratory, and Histologic Presentation and Outcome in 47 Patients. Medicine (Baltimore). 2009;88(2):98-106. doi: 10.1097/MD.0b013e31819de50f
  8. Mahfoudhi M, Mamlouk H, Turki S, Kheder A. Systemic sarcoidosis complicated of acute renal failure: about 12 cases. Pan African Med J. 2015;22:75. doi: 10.11604/pamj.2015.22.75.6237



Abstract - 45

PDF (Russian) - 9





  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Novoslobodskaya str 31c4., Moscow, 127005, Russian Federation

Managing Editor:


© 2018 "Consilium Medicum" Publishing house

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies