Successful treatment of a rare variant of mesangioproliferative glomerulonephritis with IgM deposits with Cyclosporin A

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Abstract


We present a case with a rare variant of glomerulonephritis, IgM nephropathy, which occurs mainly with nephrotic syndrome. The clinical features of this variant of kidney damage are characterized; the pathogenetic and the transformation of this form of nephritis into focal segmental glomerulosclerosis are discussed. The development of severe nephrotic syndrome at the beginning of the disease, the formation of secondary steroid resistance have confirmed this hypothesis and have justified the treatment with cyclosporin A aimed at the recovery of the function of the podocyte with remission of nephritis.


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About the authors

Daria V. Gurova

Sechenov First Moscow State Medical University (Sechenov University)

Email: natasha_tcheb@mail.ru
ORCID iD: 0000-0001-8232-3679

Russian Federation, Moscow

студентка, Клиника им. Е.М. Тареева

Natalia V. Chebotareva

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: natasha_tcheb@mail.ru
ORCID iD: 0000-0003-2128-8560

Russian Federation, Moscow

д.м.н., проф., каф. внутренних, профессиональных болезней и ревматологии, Клиника им. Е.М. Тареева

Anatoliy A. Vinogradov

Lomonosov Moscow State University

Email: natasha_tcheb@mail.ru
ORCID iD: 0000-0001-7529-0215

Russian Federation, Moscow

клинический ординатор каф. внутренних болезней

Ekaterina V. Stavrovskaya

Sechenov First Moscow State Medical University (Sechenov University)

Email: natasha_tcheb@mail.ru

Russian Federation, Moscow

доц. каф. внутренних, профессиональных болезней и ревматологии, Клиника им. Е.М. Тареева

Lidia V. Lysenko

Sechenov First Moscow State Medical University (Sechenov University)

Email: natasha_tcheb@mail.ru

Russian Federation, Moscow

д.м.н. проф., каф. внутренних, профессиональных болезней и ревматологии, Клиника им. Е.М. Тареева

References

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