IgG4-related disease: what do we know after 20 years

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Abstract


IgG4-related disease is immunomediated fibroinflammatory condition, characterized by tumefective lesions in different organs with distinctive pathomorphological features and IgG4 hypersecretion in serum and tissues in the majority of patients. IgG4-RD has been established as a separate clinical in the early 2000s. In the review we focus on the evolution of views on ethiopathogenesis of the disease, therapeutic and diagnostic options and classification of the disease.


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About the authors

E. V. Sokol

Nasonova Research Institute of Rheumatology

Author for correspondence.
Email: name.sokol@gmail.com
ORCID iD: 0000-0002-2191-9361

Russian Federation, Moscow

к.м.н., науч. сотр. лаб. интенсивных методов терапии ревматических заболеваний

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