Wasting syndrome in HIV-infected patients

Abstract


The review of literature analyzes scientific data on wasting syndrome in HIV-infected patients. It considers its etiology, diagnosis, and therapeutic approaches.

About the authors

K Ch Emerole


A V Рokrovskaya


V I Pilipenko


References

  1. Shikuma, Zackin, Sattler et al Changes in weight and lean body mass during highly active antiretroviral therapy: Clin Infect Dis. 2004;39:1223-1230. doi: 10.1086/424665.
  2. Wasserman P, Segal-Maurer S, Rubin D. Wasting Disease, Chronic Immune Activation, and Inflammation in the HIV-Infected. Patient. 2011;26:14-28. doi: 10.1097/TIN.0b013e318209e3a0.
  3. Wanke, Silva et al. Weight loss and wasting as a complication in HIV patients in the era of HAART. Clin Infect Dis. 2000;31:803-805. doi: 10.1086/314027.
  4. Palenicek JP, Graham NMH: Weight loss prior to clinical AIDS as a predictor of survival. J Acquir Immune Defic Syndr. 2004;35:367-375. doi: 10.1097/00042560-199511000-00009.
  5. Kotler DP, Tierney AR, Wang J, Pierson RN Jr. Magnitude of body-cell-mass depletion and the timing of death from wasting in AIDS. Am J Clin Nutrition. 1989;50:444-447. http://www.ncbi.nlm.nih.gov/pubmed/2773823.
  6. Tang AM, Forrester J: Weight Loss and Survival in HIV-Positive Patients in the Era of Highly Active Antiretroviral Therapy. J Acquired Immune Deficiency Syndromes. 2002;10:366-373. doi: 10.1097/01.QAI.0000026514.98625.8F.
  7. Derrick B. Jelliffe, MD, Hunger disease: Studies by the Jewish Physicians in the Warsaw Ghetto. JAMA. 1979;242(8):767. doi: 10.1001/jama.1979.03300080061035.
  8. Destsky AS, Smalley PS, Chang J: The rational clinical examination. Is this patient malnourished? JAMA. 1994;271:54-58. doi: 10.1001/jama.271.1.54.
  9. Grunfeld C, Pang M, Resting energy expenditure, calorie intake, and short term weight change in HIV and AIDS. Am J Clinical Nutrition. 1992;55:455-460. doi: 10.1177/0148607193017004392.
  10. Chandra RK. Nutrition and immunology: From the clinic to cellular biology and back again. Proc Nutr Soc. 1999;58(3):681-683. doi: 10.1017/S0029665199000890.
  11. Kim RJ, Wilson CG, Wabitsch M, Lazar MA, Steppan CM. HIV protease inhibitor-specific alterations in human adipocyte differentiation and metabolism. Obesity (Silver Spring). 2006;14:994-1002. doi: 10.1038/oby.2006.114.
  12. Riddler SA, Smit E, Cole SR et al. Impact of HIV infection and HAART on serum lipids in men. JAMA. 2003;289:2978-2982. doi: 10.1001/jama.289.22.2978.
  13. Grunfeld C, Pang M, Doerrler W, Shigenaga JK, Jensen P, Feingold KR. Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. J Clin Endocrinol Metab. 1992;74:145-152. doi: 10.1210/jcem.74.5.1373735.
  14. Friis-Moller N, Weber R, Reiss P et al. Cardiovascular disease risk factors in HIV patients-association with antiretroviral therapy. Results from the DAD study. AIDS. 2003;17:1179-1193. doi: 10.1097/00002030-200305230-00010.
  15. Jones SP, Waitt C, Sutton R, Back DJ, Pirmohamed M. Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes. AIDS. 2008;22:1293-1298. doi: 10.1097/QAD.0b013e3283021a4f.
  16. Peter J. Wasserman, Sorana Segal- Wasting Disease, Chronic Immune Activation, and Inflammation in the HIV-Infected Patient. Topics in Clinical Nutrition: 2011;26:14-28. doi: 10.1097/TIN.0b013e318209e3a0.
  17. Croxson TS, Chapman WE, Miller LK et al. Changes in the hypothalamic-pituitary-gonadal-axis in HIV infected homosexual men. Clin Endocrinol Metabol. 1989;68:317-321. doi: 10.1210/jcem-68-2-317.
  18. Brockmeyer NH, Kreuter A, Bader A, Seemann U, Reimann G. Prevalence of Endocrine Dysfunction in HIV-Infected Men. Horm Res. 2000;54:294-295. doi: 10.1159/000053274.
  19. Grinspoon S, Lee K et al. Loss of lean body and muscle mass correlates with androgen levels in hypogonodal men with AIDS and wasting syndrome. J Clin EndocrinolMetabolism. 1996;81:4051-4058. doi: 10.1210/jcem.81.11.8923860.
  20. Rietschel P, Corcoran C et al. Prevalence of hypogonadism among men with weight loss related to HIV infection who were receiving HAART. Clin Infect Dis. 2000;31:1240-1244. doi: 10.1086/317457.
  21. Dolan S, Wilkie S et al. Effects of testosterone administration in HIV- infected women with low weight: a randomized placebo-controlled study. Arm Int Med. 2004;164:897-904. doi: 10.1097/QAD.0b013e3283299145.
  22. Miller K, Corcoran C, Armstrong C et al. Transdermal testosteron administration in women with acquired immunodeficiency syndrome wasting: a pilot study. J Clin Endocrinol Metab. 1998;83:2717-2725. doi: 10.1210/jcem.83.8.5051.
  23. Smith WJ, Underwood LE. Effects of caloric restriction or protein restriction on insulin-like growth factor-1 and IGF-binding proteins in children and adults. J Clin Endocrinol Metabol. 1995;80:443-449. doi: 10.1210/jcem.80.2.7531712.
  24. Grinspoon S, Corcoran C, Stanley T et al. Effects of androgen administration on the growth hormone-insulin like growth factor1 axis in men with AIDS wasting syndrome. J Clin Endocrinol Metab. 1998;83:4251-4256. doi: 10.1210/jcem.83.12.5305.
  25. Fearon KC, Luff R. The nutritional management of surgical patients: enhanced recovery after surgery. Proc Nutr Soc. 2003;62:807-811. doi: 10.1079/PNS2003299.
  26. Baker JP et al: Nutritional assessment: A comparition of clinical judgment and objective measurments. N Eng J Ned. 1982;306:969-972. doi: 10.1056/NEJM198204223061606.
  27. Покровский В.М., Коротько Г.Ф. Обмен Веществ и Энергии Питания. Физиология Человека. 1997;10(1):475-504. http://bibliotekar.ru/447/178.htm.
  28. Stack JA, Burke PA, Forse RA. High-energy, high protein, oral, liquid, nutrition supplementation in patients with HIV infection. 1996;96:337-341. doi: 10.1016/S0002-8223(96)00095-8.
  29. Fogaca H, Souza H, Carneiro AJ et al. Effects of oral nutritional supplementation on the intestinal mucosa of patients with AIDS. J Gastroenterol. 2000;30:77-80. doi: 10.1097/00004836-200001000-00015.
  30. Berneis K, Battegay M. Nutritional supplements combined with dietary counseling in HIV-infected patients. Eur J Clin Invest. 2000;30(1)87-94. doi: 10.1046/j.1365-2362.2000.00591.
  31. Kelly O’Brien, Stephanie Nixon, Anne-Maria Tynan, Richard H. Glazier: Effectiveness of Aerobic Exercise in Adults Living with HIV/AIDS: Systematic Review. Med Sci Sports Exerc. 2004;36:1659-1666. doi: 10.1249/01.mss.0000142404.28165.9b.
  32. Jamie H Von Roenn, Donald Armstrong, Donald P Kotler, David L Cohn, Nancy G Klimas, Tchekmedyian NS, Lawrence Cone, Patrick J Brennan, Sigmund A Weitzman. Megestrol acetate in patients with AIDS and cachexia. Ann Intern Med. 1994;121(6):393-399. doi: 10.7326/0003-4819-121-6-199409150-00001.
  33. Mwamburi DM, Gerrior J, Wilson IB et al. Comparing megestrol acetate therapy with oxandrolone therapy for HIV related weight loss: similar results in 2 months. Clin Infect Dis. 2004;38:895902. doi: 10.1086/381977.
  34. Reitschel P, Hadigan C, Corcoran C et al. Assessment of growth hormone dynamics in immunodeficiency virus-related lipodystrophy. J Clin Endocrinol Metab. 2001;86:501-510. doi: 10.1210/jcem.86.2.7175.
  35. Schambelan M, Mulligan K, Grunfeld C et al. Recombinant human growth hormone in patients with HIV-associated wasting: a randomized placebo controlled trial. Ann Intern Med. 1996;125(11):873-882. doi: 10.7326/0003-4819-125-11-199612010-00002.
  36. Silverberg MJ, Leyden W, Hurley L et al. Response to newly prescribed lipid-lowering therapy in patients with and without HIV infection. Ann Intern Med. 2009;150(5):301-313. doi: 10.7326/0003-4819-150-5-200903030-00006.

Statistics

Views

Abstract - 63

PDF (Russian) - 11

Cited-By


Article Metrics

Metrics Loading ...

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
 

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Novoslobodskaya str 31c4., Moscow, 127005, Russian Federation

Managing Editor:

 

© 2018 "Consilium Medicum" Publishing house


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies