24-hour systolic wave increment index monitoring in patients with low-renin arterial hypertension


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Abstract

AIM. To analyze the circadian rhythm of blood pressure (BP) and daily reflected wave values in patients with low-renin hypertension with normal and elevated aldosterone production. MATERIALS AND METHODS. The investigation included 66 patients. 24-hour BP monitoring was carried out and arterial wall rigidity and reflected wave values were assessed in all the patients. RESULTS. The patients with hyperaldosteronemia were found to have not only statistically significant severer hypertension, impaired circadian rhythms of BP, but also impaired augmentation index (Aix) - mainly its nocturnal increase. A positive correlation was found between nocturnal Aix and resting plasma aldosterone concentrations (r=-0.31; р=0.002). CONCLUSION. The findings suggest the expediency of 24-hour systolic wave increment index monitoring in hypertensive patients of this category.

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Суточное мониторирование индекса прироста систолической волны у больных с низкорениновыми формами артериальной гипертонии. - Резюме. Цель исследования. Анализ суточного ритма артериального давления (АД) и суточных показателей отраженной волны у больных с низкорениновыми формами артериальной гипертонии (АГ) при нормальной и повышенной продукции альдостерона. Материалы и методы. В исследование включили 66 пациентов, которым проводили суточное мониторирование АД с оценкой ригидности артериальной стенки и показателей отраженной волны. Результаты. У больных с гиперальдостеронемией выявлены не только статистически значимое более тяжелое течение АГ, нарушение суточного ритма АД, но также нарушение суточного ритма индекса аугментации (AIx) - преимущественное его повышение в ночные часы. Обнаружена положительная корреляция между AIx в ночные часы и уровнем концентрации альдостерона плазмы в покое (r=-0,31; р=0,002). Заключение. Полученные результаты свидетельствуют о целесообразности суточного мониторирования индекса прироста систолической волны у больных АГ этой категории.
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