24-hour systolic wave increment index monitoring in patients with low-renin arterial hypertension

Abstract


AIM. To analyze the circadian rhythm of blood pressure (BP) and daily reflected wave values in patients with low-renin hypertension with normal and elevated aldosterone production. MATERIALS AND METHODS. The investigation included 66 patients. 24-hour BP monitoring was carried out and arterial wall rigidity and reflected wave values were assessed in all the patients. RESULTS. The patients with hyperaldosteronemia were found to have not only statistically significant severer hypertension, impaired circadian rhythms of BP, but also impaired augmentation index (Aix) - mainly its nocturnal increase. A positive correlation was found between nocturnal Aix and resting plasma aldosterone concentrations (r=-0.31; р=0.002). CONCLUSION. The findings suggest the expediency of 24-hour systolic wave increment index monitoring in hypertensive patients of this category.

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About the authors

Z S Valieva

Email: v.zarina.v@gmail.com

N M Chikhladze

A N Rogoza

E B Iarovaia

E G Bosykh

I E Chazova

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