Current views on the role of probiotics in the prevention and treatment of different diseases: Focus on Linex


Cite item

Full Text

Abstract

The paper gives documentary information on the role of probiotics in the therapy of different diseases and recommendations for their use. The efficacy and safety of the combined probiotic Linex are discussed on the basis of the results of clinical trials.

Full Text

Современные представления о роли пробиотиков в профилактике и лечении различных заболеваний: фокус на Линекс. - Аннотация. В статье представлены доказательные данные о роли пробиотиков в терапии различных заболеваний и рекомендации по их применению. На основании результатов клинических исследований обсуждается эффективность и безопасность комбинированного пробиотика Линекс.
×

About the authors

E A Ushkalova

Email: eushk@yandex.ru

References

  1. Парфенов А.И., Бондаренко В.М. Что нам дал вековой опыт познания симбионтной кишечной микрофлоры. Тер арх 2012; 2: 5-10.
  2. Prakash S., Rodes L., Coussa-Charley M., Tomaro-Duchesneau C. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics 2011; 5: 71-86.
  3. Floch M.H., Walker W.A., Madsen K. et al. Recommendations for probiotic use-2011 update. J Clin Gastroenterol 2011; 45: 168-171.
  4. World Gastroenterology Organisation Practice Guideline. Probiotics and prebiotics May 2008.
  5. Wang Z.H., Gao Q.Y., Fang J.Y. Meta-analysis of the efficacy and safety of Lactobacillus-containing and Bifidobacterium-containing probiotic compound preparation in Helicobacter pylori eradication therapy. J Clin Gastroenterol 2013; 47 (1): 25-32.
  6. Zheng X., Lyu L., Mei Z. Lactobacillus-containing probiotic supplementation increases Helicobacter pylori eradication rate: Evidence from a meta-analysis. Rev Esp Enferm Dig 2013; 105 (8): 445-453.
  7. Zou J., Dong J., Yu X. Meta-analysis: Lactobacillus containing quadruple therapy versus standard triple first-line therapy for Helicobacter pylori eradication. Helicobacter. 2009; 14 (5): 97-107.
  8. Li S., Huang X.L., Sui J.Z. et al. Meta-analysis of randomized controlled trials on the efficacy of probiotics in Helicobacter pylori eradication therapy in children. Eur J Pediatr 2014; 173 (2): 153-161.
  9. Хавкин А.И., Блат С.Ф. Роль пробиотической терапии при инфекции Helicobacter pylori у детей. Детские инфекции 2008; 4: 53-58.
  10. Хавкин А.И., Жихарева Н.С. Терапия антибиотик-ассоциированного дисбактериоза. Рус мед журн 2006; 19: 12.
  11. Deshpande G., Rao S., Patole S. et al. Updated meta-analysis of probiotics for preventing necrotizing enterocolitis in preterm neonates. Pediatrics 2010; 125: 921-930.
  12. Wang Q., Dong J., Zhu Y. Probiotic supplement reduces risk of necrotizing enterocolitis and mortality in preterm very low-birth-weight infants: an updated meta-analysis of 20 randomized, controlled trials. J Pediatr Surg 2012; 47 (1): 241-248.
  13. Alfaleh K., Anabrees J., Bassler D., Al-Kharfi T. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database Syst Rev 2011; 3: CD005496.
  14. Bernardo W.M., Aires F.T., Carneiro R.M. et al. Effectiveness of probiotics in the prophylaxis of necrotizing enterocolitis in preterm neonates: a systematic review and meta-analysis. J Pediatr (Rio J) 2013; 89 (1): 18-24.
  15. Deshpande G.C., Rao S.C., Keil A.D., Patole S.K. Evidence-based guidelines for use of probiotics in preterm neonates. BMC Med 2011; 9: 92.
  16. Downard C.D., Renaud E., St Peter S.D. et al. Treatment of necrotizing enterocolitis: an American Pediatric Surgical Association Outcomes and Clinical Trials Committee systematic review. J Pediatr Surg 2012; 47 (11): 2111-2222.
  17. Salminen S., Nybom S., Meriluoto J. et al. Interaction of probiotics and pathogens - benefits to human health? Curr Opin Biotechnol 2010; 21: 157-167.
  18. Сухорукова М.В., Тимохова А.В., Эйдельштейн М.В., Козлов Р.С. Чувствительность к антибиотикам штаммов бактерий, входящих в состав пробиотика "Линекс". Клин микробиол антимикроб химиотер 2012; 3: 245-251.
  19. Anabrees J., Indrio F., Paes B., Alfaleh K. Probiotics for infantile colic: a systematic review. BMC Pediatr 2013; 13 (1): 186.
  20. McFarland L.V., Dublin S. Meta-analysis of probiotics for the treatment of irritable bowel syndrome. World J Gastroenterol 2008; 17: 2650-2661.
  21. Hoveyda N., Heneghan C., Mahtani K.R. et al. A systematic review and meta-analysis: probiotics in the treatment of irritable bowel syndrome. BMC Gastroenterol 2009; 9: 15.
  22. Moayyedi P., Ford A.C., Talley N.J. et al. The efficacy of probiotics in the treatment of irritable bowel syndrome: a systematic review. Gut 2010; 59 (3): 325-332.
  23. Ortiz-Lucas M., Tobhas A., Saz P. et al. Effect of probiotic species on irritable bowel syndrome symptoms: A bring up to date meta-analysis. Rev Esp Enferm Dig 2013; 105 (1): 19-36.
  24. Nikfar S., Rahimi R., Rahimi F. Efficacy of probiotics in irritable bowel syndrome: a meta-analysis of randomized, controlled trials. Dis Colon Rectum 2008; 51 (12): 1775-1780.
  25. Парфенов А.И., Ручкина И.Н., Атауллаханов Р.И. Постинфекционные синдром раздраженного кишечника. Особенности патогенеза, диагностики и лечения. Рус мед журн 2010; 11: 2.
  26. Ford A., Vandvik P. Irritable bowel syndrome. Clin Evid (Online) 2012; 2012: pii: 0410.
  27. Simrén M., Barbara G., Flint H.J. et al. Intestinal microbiota in functional bowel disorders: a report. Gut 2013; 62 (1): 159-176.
  28. Scaldaferri F., Gerardi V., Lopetuso L.R. et al. Gut microbial flora, prebiotics, and probiotics in IBD: their current usage and utility. Biomed Res Int 2013; 2013: 435268.
  29. Chapman T., Plosker G., Figgitt D. VSL#3 probiotic mixture: a review of its use in chronic inflammatory bowel diseases. Drugs 2006; 66 (10): 1371-1387.
  30. Shen J., Zuo Z.X., Mao A.P. Effect of Probiotics on Inducing Remission and Maintaining Therapy in Ulcerative Colitis, Crohn’s Disease, and Pouchitis: Meta-analysis of Randomized Controlled Trials. Inflamm Bowel Dis 2014; 20 (1): 21-35.
  31. Müllner K., Miheller P., Herszényi L., Tulassay Z. Probiotics in the Management of Crohn’s Disease and Ulcerative Colitis. Curr Pharm Des 2013 Oct 14. [Epub ahead of print].
  32. Bonis P., LaMont J., Rutgeerts P. et al. Approach to the adult with chronic diarrhea in developed countries. Uptodate June 2011. http://www.uptodate.com/contents/approach-to-the-adult-with-chronic-diarrhea-in-developed-countries?source=see_link4
  33. Wasilewska E., Złotkowska D., Pijagin M.E. The role of intestinal microflora and probiotic bacteria in prophylactic and development of colorectal cancer. Postepy Hig Med Dosw (Online). 2013; 67: 837-847.
  34. Uccello M., Malaguarnera G., Basile F. et al. Potential role of probiotics on colorectal cancer prevention. BMC Surg 2012; 12 Suppl 1: S35.
  35. Wilt T.J., Shaukat A., Shamliyan T. et al. Lactose intolerance and health. Evid Rep Technol Assess (Full Rep) 2010; 192: 1-410.
  36. Shaukat A., Levitt M.D., Taylor B.C. et al. Systematic review: effective management strategies for lactose intolerance. Ann Intern Med 2010; 152 (12): 797-803.
  37. Henao-Mejia J., Elinav E., Thaiss C.A. et al. Role of the intestinal microbiome in liver disease. J Autoimmun 2013; 46: 66-73.
  38. Jover-Cobos M., Khetan V., Jalan R. Treatment of hyperammonemia in liver failure. Curr Opin Clin Nutr Metab Care 2014; 17 (1): 105-110.
  39. McGee R.G., Bakens A., Wiley K. et al. Probiotics for patients with hepatic encephalopathy. Cochrane Database Syst Rev 2011; 11: CD008716.
  40. Mohammad R.A., Regal R.E., Alaniz C. Combination therapy for the treatment and prevention of hepatic encephalopathy. Ann Pharmacother 2012; 46 (11): 1559-1563.
  41. Younossi Z.M., Reyes M.J., Mishra A. et al. Systematic review with meta-analysis: non-alcoholic steatohepatitis - a case for personalised treatment based on pathogenic targets. Aliment Pharmacol Ther 2014; 39 (1): 3-14.
  42. Kelishadi R., Farajian S., Mirlohi M. Probiotics as a novel treatment for non-alcoholic Fatty liver disease; a systematic review on the current evidences. Hepat Mon 2013 Apr 9;13(4):e7233
  43. Ma Y.Y., Li L., Yu C.H. et al. Effects of probiotics on nonalcoholic fatty liver disease: A meta-analysis. World J Gastroenterol 2013; 19 (40): 6911-6918.
  44. Wang Y., Liu Y., Kirpich I. Lactobacillus rhamnosus GG reduces hepatic TNF? production and inflammation in chronic alcohol-induced liver injury. J Nutr Biochem 2013; 24 (9): 1609-1615.
  45. Wang Y., Kirpich I., Liu Y. et al. Lactobacillus rhamnosus GG treatment potentiates intestinal hypoxia-inducible factor, promotes intestinal integrity and ameliorates alcohol-induced liver injury. Am J Pathol 2011; 179 (6): 2866-2875.
  46. Селиверстов П., Радченко В., Сафроненкова И., Ситкин С. Взаимоотношения печени и кишечника на фоне дисбаланса микрофлоры толстой кишки. Врач 2009; 10: 12.
  47. Kim N.Y., Ji G.E. Effects of probiotics on the prevention of atopic dermatitis. Korean J Pediatr 2012; 55 (6): 193-201.
  48. Lee J., Seto D., Bielory L. Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitis. J Allergy Clin Immunol 2008; 121 (1): 116-121.
  49. Foolad N., Brezinski E.A., Chase E.P., Armstrong A.W. Effect of nutrient supplementation on atopic dermatitis in children: a systematic review of probiotics, prebiotics, formula, and fatty acids. JAMA Dermatol 2013; 149 (3): 350-355.
  50. Elazab N., Mendy A., Gasana J. et al. Probiotic administration in early life, atopy, and asthma: a meta-analysis of clinical trials. Pediatrics 2013; 132 (3): e666-676.
  51. Tang L.J., Chen J., Shen Y. [Meta-analysis of probiotics preventing allergic diseases in infants]. Zhonghua Er Ke Za Zhi 2012; 50 (7): 504-509.
  52. Dang D., Zhou W., Lun Z.J. et al. Meta-analysis of probiotics and/or prebiotics for the prevention of eczema. J Int Med Res 2013; 41 (5): 1426-1436.
  53. Das R.R., Naik S.S., Singh M. Probiotics as additives on therapy in allergic airway diseases: a systematic review of benefits and risks. Biomed Res Int 2013; 2013: 231979.
  54. Усенко Д.В. Острые кишечные инфекции у детей с атопическим дерматитом: клинико-иммунологические особенности, тактика терапии и иммунореабилитации: Автореф. дис. ... д-ра мед. наук. М 2013; 44.
  55. Foisy M., Boyle R.J., Chalmers J.R. et al. The prevention of eczema in infants and children: an overview of Cochrane and non-Cochrane reviews. Evid Based Child Health 2011; 6 (5): 1322-1339.
  56. Hao Q., Lu Z., Dong B.R. et al. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev 2011 9: CD006895.
  57. Kang E.J., Kim S.Y., Hwang I.H., Ji Y.J. The effect of probiotics on prevention of common cold: a meta-analysis of randomized controlled trial studies. Korean J Fam Med 2013; 34 (1): 2-10.
  58. Petrof E.O., Dhaliwal R., Manzanares W. et al. Probiotics in the critically ill: a systematic review of the randomized trial evidence. Crit Care Med 2012; 40 (12): 3290-3302.
  59. Liu K.X., Zhu Y.G., Zhang J. et al. Probiotics’ effects on the incidence of nosocomial pneumonia in critically ill patients: a systematic review and meta-analysis. Crit Care 2012; 16 (3): R10.
  60. Barraud D., Bollaert P.E., Gibot S. Impact of the administration of probiotics on mortality in critically ill adult patients: a meta-analysis of randomized controlled trials. Chest 2013; 143 (3): 646-655.
  61. Kinross J.M., Markar S., Karthikesalingam A. et al. A meta-analysis of probiotic and synbiotic use in elective surgery: does nutrition modulation of the gut microbiome improve clinical outcome? JPEN J Parenter Enteral Nutr 2013; 37 (2): 243-253.
  62. Pitsouni E., Alexiou V., Saridakis V. et al. Does the use of probiotics/synbiotics prevent postoperative infections in patients undergoing abdominal surgery? A meta-analysis of randomized controlled trials. Eur J Clinharmacol 2009; 65 (6): 561-570.
  63. Grin P.M., Kowalewska P.M., Alhazzan W. et al. Lactobacillus for preventing recurrent urinary tract infections in women: meta-analysis. Can J Urol 2013; 20 (1): 6607-6614.
  64. Sekar U., Shanthi M. Blastocystis: Consensus of treatment and controversies. Trop Parasitol 2013; 3 (1): 35-39.
  65. Dinleyici E.C., Eren M., Dogan N. et al. Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystishominis infection. Parasitol Res 2011; 108 (3): 541-545.
  66. Besirbellioglu B.A., Ulcay A., Can M. et al. Saccharomyces boulardii and infection due to Giardia lamblia. Scand J Infect Dis 2006; 38 (6-7): 479-481.
  67. Корниенко Е.А. Современные диагностика и лечение лямблиоза у детей. Consilium medicum 2010; 1: 25.
  68. Сигидаев А.С. Клинико-лабораторная характеристика бластоцистной инвазии у больных HCV-инфекцией: Автореф. дис. … канд. мед. наук. СПб 2012; 17.
  69. Firouzi S., Barakatun-Nisak M.Y., Ismail A. et al. Role of probiotics in modulating glucose homeostasis: evidence from animal and human studies. Int J Food Sci Nutr 2013; 64 (6): 780-786.
  70. Lindsay K.L., Walsh C.A., Brennan L., McAuliffe F.M. Probiotics in pregnancy and maternal outcomes: a systematic review. J Matern Fetal Neonatal Med 2013; 26 (8): 772-778.
  71. Vandevusse L., Hanson L., Safdar N. Perinatal outcomes of prenatal probiotic and prebiotic administration: an integrative review. J Perinat Neonatal Nurs 2013; 27 (4): 288-301.
  72. Luoto R., Kalliomaki M., Laitinen K., Isolauri E. The impact of perinatal probiotic intervention on the development of overweight and obesity: follow-up study from birth to 10 years. Int J Obes 2010; 16: on line.
  73. Million M., Angelakis E., Paul M. et al. Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals. Microb Pathog 2012; 53 (2): 100-108.
  74. Sanaie S., Ebrahimi-Mameghani M., Mahmoodpoor A. et al. Effect of a Probiotic Preparation (VSL#3) on Cardiovascular Risk Parameters in Critically-Ill Patients. J Cardiovasc Thorac Res 2013; 5 (2): 67-70.
  75. Rossi M., Klein K., Johnson D.W., Campbell K.L. Pre-, pro-, and synbiotics: do they have a role in reducing uremic toxins? A systematic review and meta-analysis. Int J Nephrol 2012; 2012: 673631.
  76. Cagetti M.G., Mastroberardino S., Milia E. et al. The use of probiotic strains in caries prevention: a systematic review. Nutrients 2013; 5 (7): 2530-2550.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2014 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
 

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Managing Editor:

  • Tel.: +7 (926) 905-41-26
  • E-mail: e.gorbacheva@ter-arkhiv.ru

 

 © 2018-2021 "Consilium Medicum" Publishing house


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies