Contrast-induced nephropathy

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The increasing number of invasive procedures done with contrast agents makes the prevention of their induced nephropathy more urgent. At present, different methods are being developed to prevent contrast-induced nephropathy (CIN) with antioxidants, intrarenal vasodilators, hydration therapy, by accurately determining the amount of excreted fluid obtained from a urinary catheter and less toxic iodine-containing contrast agents are being put into practice. Unfortunately, the current guidelines for the prevention of CIN are inadequately followed in both Russia and foreign countries. This review covers the main components of the pathogenesis and risk factors of this pathology and its possible preventive measures.

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Индуцированная контрастными веществами нефропатия. - Аннотация. С увеличением количества инвазивных вмешательств, проводимых с применением контрастных веществ (КВ), профилактика вызванной ими нефропатии становится все более актуальной. В настоящее время разрабатываются различные методы профилактики индуцированной КВ нефропатии (ИКВН) с применением антиоксидантов, интраренальным введением вазодилататоров, проведением гидратационной терапии в соответствии с точным определением количества полученной по мочевому катетеру выделенной жидкости, а также внедрение в практику менее токсичных содержащих йод КВ. К сожалению, современные рекомендации по профилактике ИКВН соблюдаются клиницистами в недостаточной степени как в России, так и за рубежом. Данный обзор освещает основные звенья патогенеза, факторы риска развития и меры возможной профилактики этой патологии.

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O Iu Mironova


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