Cardiorenal links in systemic amyloidosis


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Abstract

The paper gives current general data on the structure of amyloid fibril and the principles in the classification of amyloidosis, information on the clinical course of cardiac and renal involvements in systemic AL and AA amyloidosis, and that on diagnostic and prognostic criteria and the specific features of cardiorenal links. The authors draw the conclusion that the identification of acute and chronic cardiorenal links is of practical value for systemic amyloidosis. Cardiorenal and renocardiac syndromes are not always differentiated clearly in the systemacy of involvement.

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Кардиоренальные взаимосвязи при системном амилоидозе. - Аннотация. Приведены современные общие данные о структуре амилоидной фибриллы, принципах классификации амилоидоза, сведения о клиническом течении поражения сердца и почек при системном AL- и АА-амилоидозе, критериях диагностики и прогноза, особенностях кардиоренальных взаимосвязей. Авторы делают вывод, что в отношении системного амилоидоза практическое значение имеет выделение острого и хронического вариантов кардиоренальных взаимосвязей. Кардиоренальный и ренокардиальный синдромы не всегда четко дифференцируются в условиях системности поражения.
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