Gluten-sensitivity celiac disease associated with recurrent aphthous stomatitis and schizophrenia


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Abstract

The paper describes a clinical case of celiac disease with grade 3 malabsorption, which is associated with recurrent aphthous stomatitis and schizophrenia. On readmission after 8 months of strict adherence to his gluten-free diet, the patient was observed to be in clinical remission and to have normalized laboratory indices and immunological tests. The signs of recurrent stomatitis disappeared. However, the symptoms of the mental disease remained.

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Чувствительная к глютену целиакия, ассоциированная с рецидивирующим афтозным стоматитом и шизофренией. - Аннотация. Представлен клинический случай целиакии с синдромом нарушенного всасывания III степени тяжести, ассоциированной с рецидивирующим афтозным стоматитом и шизофренией. При повторной госпитализации через 8 мес строгого соблюдения аглютеновой диеты у больного наблюдались клиническая ремиссия, нормализация лабораторных показателей и иммунологических проб. Исчезли явления рецидивирующего стоматита. Однако сохранялись симптомы психического заболевания.
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References

  1. Парфенов А.И. Энтерология. М: МИА 2009; 886.
  2. Field E.A., Allan R.B. Review article oral ulceration- aetiopathogenesis clinical diagnosis and management in the gastrointestinal clinic. Aliment Pharmacol Ther 2003; 18 (10): 949-962.
  3. Scully C., Porter S. Oral mucosal disease recurrent aphthous stomatitis. Br J Oral Maxillotac Surg 2008; 46 (3): 198-206.
  4. Femiano F., Lanza A., Buonaiuto C. et al. Guidelines for diagnosis and management of aphthous stomatitis. Pediatr Infect Dis J 2007; 26 (8): 728-732.
  5. Barrons R.W. Treatment strategias for recurrent oral aphthous ulcers. Am J Helth Syst Pharm 2001; 58 (1): 41-50.
  6. Straub R.E., MacLean C.J., O'Neill F.A. et al. A potential vulnerability locus for schizophrenia on chromosome 6p24-22: evidence for genetic heterogeneity. Nature Genet 1995; 11: 287-293
  7. Zhong F., McCombs C.C., Olson J.M. et al. An autosomal screen for genes that predispose to celiac disease in the western counties of Ireland. Nature Genet 1996; 14: 329-333.
  8. Eaton W., Byrne M, Ewald H. et al. Association of schizophrenia and autoimmune diseases: linkage of Danish national registers. Am J Psychiatr 2006; 163 (3): 521-528.
  9. Kalaydjian A.E., Eaton W., Cascella N., Fasano A. The gluten connection: the association between schizophrenia and celiac disease. Acta Psychiatr Scand 2006; 113: 82-90.
  10. Eaton W., Mortensen P., Agerbo E. et al. Coeliac disease and schizophrenia: population based case control study with linkage of Danish national registers. Br Med J 2004; 328 (7437): 438-439.

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