Blood pressure variability and risk for complications in arterial hypertension

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The lecture gives the definition and lists the types of blood pressure variability. It considers the importance of different types of blood pressure variability as an independent risk factor of complications in arterial hypertension. There is an update on the impact of antihypertensive drug therapy on blood pressure variability.

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Вариабельность артериального давления и риск развития осложнений при артериальной гипертонии. - Аннотация. В лекции приведено определение и перечислены виды вариабельности артериального давления. Рассмотрено значение разных видов вариабельности артериального давления как независимого фактора риска развития осложнений при артериальной гипертонии. Приведены современные данные литературы о влиянии медикаментозной антигипертензивной терапии на вариабельность артериального давления.

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O D Ostroumova



  1. Rothwell P.M., Howard S.C., Dolan E. et al. Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension. Lancet 2010; 375: 895-905.
  2. Sever P.S., Dahlof B., Poulter N.R. et al. Rationale, design, methods and baseline demography of participants of the Anglo-Scandinavian Cardiac Outcomes Trial. J Hypertens 2001; 6: 1139-1147.
  3. Dahlof B., Sever P.S., Poulter N.R. et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in Anglo-Scandinavian Cardiac Outcomes Trial - Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentral randomized controlled trial. Lancet 2005; 366: 895-906.
  4. Verdecchia P., Angeli F., Gattobigio R. et al. Impact of Blood Pressure Variability on Cardiac and Cerebrovascular Complications in Hypertension. Am J Hypertens 2007; 20: 154-161.
  5. Webb A.J.S., Fischer U., Mehta Z., Rothwell P.M. Effects of antihypertensive-drug class on interindividual variation in BP and risk of stroke: a systematic review and meta-analysis. Lancet 2010; 375: 906-915.
  6. Rothwell P.M., Webb A.J.S. Effect of dose and combination of antihypertensives on interindividual blood pressure variability: A systematic review. Stroke 2011; 42: 2860-2865.
  7. Диагностика и лечение артериальной гипертензии. Российские рекомендации (четвертый пересмотр). Системные гипертензии 2010; 3: 5-26.
  8. Rothwell P.M., Howard S.C., Dolan E. et al.; ASCOT-BPLA and MRC Trial Investigators. Effects of beta-blockers and calcium-channel blockers on within individual variability in blood pressure and risk of stroke. Lancet Neurol 2010; 9: 469-480.

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