Email this article 
Hypomagnesemia in patients with chronic alcoholism in thecourse of alcohol withdrawal syndrome
- Authors: Stasyukinene VR1, Pihinis VK1, Reingardene DI1
-
Affiliations:
- Issue: Vol 79, No 11 (2004)
- Pages: 97-99
- Section: Editorial
- URL: https://ter-arkhiv.ru/0040-3660/article/view/29977
- ID: 29977
Cite item
Full Text
Abstract
Aim. To ascertain hypomagnesemia (HM) rate in patients with chronic alcoholism (CA) with alcohol
withdrawal syndrome (AWS); correlation between AWS severity and HM rate.
Material and methods. Mg in plasm was measured at photometry in 129 CA patients treated in Kaunas
Mental Hospital.
Results. Plasma Mg in CA patients with A WS was reduced (< 0.749 mmol/l), normal (0.750-1.250
mmol/l) or high (> 1.251 mmol/l) in 28.7, 65.1 and 6.2% patients, respectively. HM was diagnosed
in 42.3% with a severe, 19.1% with a moderate and 20.0% with weak AWS.
Conclusion. HM in AWS was registered in 28.7% patients. It occurred significantly more frequently
(p < 0.05) in patients with a severe AWS. Pathogenetic mechanisms of HM in AWS are described
withdrawal syndrome (AWS); correlation between AWS severity and HM rate.
Material and methods. Mg in plasm was measured at photometry in 129 CA patients treated in Kaunas
Mental Hospital.
Results. Plasma Mg in CA patients with A WS was reduced (< 0.749 mmol/l), normal (0.750-1.250
mmol/l) or high (> 1.251 mmol/l) in 28.7, 65.1 and 6.2% patients, respectively. HM was diagnosed
in 42.3% with a severe, 19.1% with a moderate and 20.0% with weak AWS.
Conclusion. HM in AWS was registered in 28.7% patients. It occurred significantly more frequently
(p < 0.05) in patients with a severe AWS. Pathogenetic mechanisms of HM in AWS are described
References
- Саг С., Holzbach E. Reversible hypokalemia and Hypomagnesemia during alcohol withdrawal syndrome. Nervenarzt 1994; 65:206-211.
- Caysen G., North R H. The effects of alcohol on blood pressure and electrolytes. Med. Clin. N. Am. 1984; 68: 221-246.
- Cunha D. F., Monteiro J. P., Ortega L. S. et al. Serum electrolytes in hospitalized pellagra alcoholics. Eur. J. Clin. Nutr. 2000; 54 (5): 440-442.
- Elisaf M. S., Siamopoulos К. С. Disorders of water; electrolyte and acid - base balance in alcoholic patients. Clin. Nephrol. 1998; 50 (6): 390-399.
- Kino M., Imanitehi H. Cardiovascular status in asymptomatic alcoholics. Br. Heart J. 1981; 46: 545-551.
- Elisaf M., Merkouropoulos M., Tsianos E. V., Siamopoulos К. С Pathogenetic mechanisms of hypomagnesemia in alcoholic patients. J. Trace Elements Med. Biol. 1995; 9: 210-214.
- Jermain D. M., Crismon M. L., Nisbeck R. P. Controversies over the use of magnesium sulfate in delirium tremens. Am. Pharmacother. 1998; 26: 650-652.
- Marotta F., Hada R., Morello P. et al. Severe electrolyte abnormalities and paralytic ileus complicating delirium tremens.Keio J. Med 1998; 38: 53-59.
- Rodrigo R., Thielemann L., Olea M. Effect of ethanol ingestion on renal regulation of water and electrolytes. Arch. Med. Res. 1998; 29: 209-218.
- Glauser J., Brady W. J. Atrial fibrillation. Geriatr. Emerg. Med. Rep. 2001; 2: 56-58.
- Tso E. L., Barich R. A. Magnesium clinical considerations. J. Emerg. 1998; 10 (6): 735-745.
- Wolfe S. M., Victor M. The relationship of hypomagnesemia and alkalosis to alcohol withdrawal syndrome. Ann. N. Y. Acad. Sci. 1969; 102: 973-983.
- Sullivan J. P., Lankford H. G., Robertson P. Renal excretion of lactate and magnesium in alcoholism. Am. J. Clin. Nutr. 1966; 18: 231-236.
- Jem S., Jagenburg R. Influence of adrenergic activity and magnesium depletion on cardiac rhythm in alcohol withdrawal. Br.Heart J. 1994; 72: 554-558.
- Joborn H., Akerstrom G., Ljunghall S. Effects of exogenous catecholamines and exercise on plasma magnesium concentrations. Clin. Endocrinol. 1985; 23: 219-226
