A course of coronary heart disease and quality of life in patients with varying depressivestates

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Aim. To study a course of coronary heart disease (CHD) in patients with depressive disorders.
Material and methods. The trial included 77 CHD patients aged 39 to 68 years (mean age
54.9 + 0.9 years), 40 (51,9%) of them had myocardial infarction. All the examinees had effort angina
of functional class II-IV by criteria of the Canadian Cardiology Association. All the patients have undergone standard clinical examination, stress tests, coronaroangiography (n = 30), assessment of the
degree of vegetative dystonia and quality of life. The patients were divided into two groups depending
on the depression degree.
Results. CHD patients with manifest depression vs those with subclinical depression had a higher level
of personality and reactive anxiety. They had neurotic and psychopathological personality alterations
associated with more pronounced vegetative disorders.
These patients suffered from more severe coronary atherosclerosis, more hospitalizations for the previous year, more myocardial infarctions, lower physical activity and quality of life.
Conclusion. CHD patients with manifest depression have lower physical performance and quality of
life though this is not confirmed at exercise tests.


  1. Kubzansky L. D., Kawachi I. Going to the heart of the matter do negative emotions cause coronary heart disease? J. Psychosom. Res. 2000; 48 (4-5): 323-337.
  2. Carney R. M., Freedland K. E., Sheline Y. L, Weiss E. S. Depression and coronary heart disease: a review for cardiologists. Clin. Cardiol. 1997; 20 (3): 196-200.
  3. Смулевич А. Б. Депрессии в общемедицинской практике. М.: Берег; 2000.
  4. Carney R. M., Freedland К. Е., Stein P. К. et al. Change in heart rate and heart rate variability during treatment for depression in patients with coronary heart disease. Psychosom. Med. 2000; 62 (5): 639-647.
  5. Sullivan M., La Croix A., Russo J. et al. Depression in coro nary heart disease. What is the appropriate diagnostic threshold? Psychosomatics 1999; 40 (4): 286-292.
  6. Appels A. Depression and coronary heart disease: observations and questions. J. Psychosom. Res. 1997; 43 (5): 443-452.
  7. Зайцев В. П. Вариант психологического теста Mini-Mult. Психол. журн. 1981; 3: 118-123.
  8. Ханин Ю. Л. Краткое руководство к применению шкалы реактивной и личностной тревожности Ч. Д. Спилбергера. Л.: ЛНИИТЕК; 1976.
  9. Веек А. Т., Ward С. Н., Mendelson M. et al. An inventory for measuring depression. Arch. Gen. Psychiatry 1961; 5: 561- 571.
  10. Holmes T. H., Rahe R. H. The social readjustment rating scale.J. Psychosom. Res. 1967; 11 (2): 213-218
  11. . Вегетативные расстройства: Клиника, лечение, диагностика / Под ред. А. М. Вейна. М.: Мед. информ. агентство; 2000.
  12. Заболевания вегетативной нервной системы / Вейн А. М.,Вознесенская Т. Г., Голубев В. Л. и др.; под ред. А. М. Вейна. М.: Медицина; 1991.
  13. Spertus J. A., Winder J. A., Dewhurst Т. A. et al. Development and evaluation of the Seattle Angina Questionnaire: a new functional status measure for coronary artery disease. J. Am. Coll. Cardiol. 1995; 25 (2): 333-341.
  14. Сыркин А. Л., Печерина Е. А., Дриницина С. В. Валидизция методик оценки качества жизни у больных стабилной стенокардией. Клин. мед. 2001; 11: 22-25.
  15. Реброва О. /О. Статистический анализ медицинских данных. Применение пакета прикладных программ STATI! TICA. М.: Медиа Сфера; 2002.

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