Quality of life, clinical symptoms and nasa! passability in patients with allergic rhinitis


Aim. To examine correlations between quality of life, impairment of nasal passability and severity of clinical symptoms in patients with allergic rhinitis (AR).
Material and methods. The examination of 54 AR patients (41 females, 13 males age 18-62 years, mean age 38 years) diagnosed seasonal AR in 19 and year-round AR in 35 patients. Quality of life was assessed by RQLQ questionnaire. Nasal inspiratory peakflowmetry was used to assess nasal obstruction. AR symptoms were registered by self-control score method.
Results. Most parameters of quality of life of AR patients correlated significantly with severity of clinical symptoms, the degree of nasal passability. Positive changes in clinical symptoms, nasal peakflowmetry evidence correlated with improvement of life quality in the course of treatment with a present-day antihistamine drug fexofenadin (120 mg/day) for 28 days.
Conclusion. Quality of life in AR patients correlated with severity of clinical symptoms and the degree of nasal obstruction. Assessment of life quality should be included in the scheme of standard examination of AR patients.

About the authors

A V Emelyanov

Т Е Trendeleva


  1. The WHOQOL Group. What is quality of life? Wld Hlth Forum 1996; 17: 354-356.
  2. Сенкевич Н. Ю., Белевский А. С., Чучалин А. Г. Оценка влияния образовательных программ в пульмонологии на Качество Жизни больных бронхиальной астмой (первый опыт применения в России опросника SF-36 в пульмонологии). Пульмонология 1997; 3: 18-22.
  3. Wenger N. К., Mattson M. E., Furberg С. D., Elinslon J. Preface and overview: assessment of quality of life in clinical trials of cardiovascular disease. In: Wenger N. K. et al., eds. Assessment of quality of life in clinical trials of cardiovascular therapies. New York; 1984. 191-205.
  4. Jumper E. F., Guyaff G. H. Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis. Clin. Exp. Allergy 1991; 21 (1): 77-83.
  5. Thompson A. K., Juniper E., Meltzer E. O. Quality of life in patients with allergic rhinitis. Allergy Asthma Immunol. 2000; 85 (5): 338-347.
  6. Ware J. E., Sherbourne С. D. The MOS 36-item short-form health survey (SF-36). 1. Conceptual framework and item selection. Med. Care 1992; 30: 473-483.
  7. Bagenstose S. E., Bernstein J. A. Treatment of chronic rhinitis by an allergy specialist improves quality of life outcomes. Ann. Allergy Asthma Immunol. 1999; 83 (6, pt 1): 524-528.
  8. Melter E. O., Casale Т. В., Nathan R. A., Thompson A. K. Once-daily fexofenadine HCL improves quality of life and reduces work and activity impairment in patients with seasonal allergic rhinitis. Ibid. (4): 311-317.
  9. Kroner В., Klimek L., Bullinger M., Mosges R. Generic or disease-specific quality of life scales to characterize health status in allergic rhinitis? Allergy 2001; 56 (10): 957-963.
  10. Juniper E. F. Rhinitis and quality of life. Eur. Respir. Rev. 1997; 7 (47): 300-302.
  11. Juniper E. F., Thompson A. K., Ferrie P. S., Roberts J. N. Development and validation of the mini Rhinoconjunctivitis Quality of Life Questionnaire. Clin. Exp. Allergy 2000; 30 (L): 132-140.
  12. International consensus report on diagnosis and management of rhinitis. Allergy 1994; 49 (suppl. 19): 1-34.
  13. Van Cauwenberge P., Bachert C., Passalacqua G. et al. Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology. Ibid. 2000; 55 (2): 116-134.
  14. Bousquet J., van Cauwenberge P., Khaltaev N. Allergic rhinitis and its impact on asthma. J. Allergy Clin. Immunol. 2001; 108 (5, pt2): 147-154.



Abstract - 75


Article Metrics

Metrics Loading ...


  • There are currently no refbacks.

Copyright (c) 2004 Emelyanov A.V., Trendeleva Т.Е.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Novoslobodskaya str 31c4., Moscow, 127005, Russian Federation

Managing Editor:


© 2018 "Consilium Medicum" Publishing house

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies