Affection of the heart in patients with psoriatic arthritis

Abstract


Aim. To examine the rate and features of heart damage in psoriatic arthritis (PA) patients and find out whether some parameters of PA are associated with cardiac involvement.
Material and methods. The study enrolled 370 PA patients aged 15 to 72 years with the disease history 1 to 44 years having different variants of the articular and skin syndromes. The patients have undergone various tests including chest x-ray, ECG, echocardiography.
Results. Myocarditis, adhesive pericarditis, valvular defects (mitral, aortic and combined mitral-aortic were diagnosed in 15.9, 18.2 and 5.7% of PA patients, respectively). Aortitis was detected in 51.3% patients with advanced sacroileitis and alky/osing spondylarthritis. Alterations in the heart were associated with spinal lesions, other systemic manifestations, activity of the disease and, in a lesser degree, with carriage of HLA-B27.
Conclusion. Cardiac syndrome in PA is characterized by marked heterogeneity and is one of basic systemic manifestations of this disease. Latent PA aortatis can be detected at echocardiography.

About the authors

V V Badokin

G P Kotelnikova

References

  1. Moll J. M. H. The place of psoriatic arthritis in the spondyloarthritides. Bailliere's Clin. Rheumatol. 1994; 8: 395-417.
  2. Stafford L., Youssef P. P. Spondyloarthropathies: an overview. Intern. Med. 2002; 1 (1-2): 40-46.
  3. Angulo J., Esplnoza L. R. The spectrum of skin, mucosa and other extraarticular manifestations in spondylarthropathies. Baillere's Clin. Rheumatol. 1998; 12 (46): 649-664.
  4. Довжанский С. И., Утц С. Р. Псориаз или псориатическая болезнь. Саратов: Изд-во Саратов, ун-та; 1992; ч. 1.
  5. Шлопов В. Г., Шевченко Т. И. Клинико-морфологический анализ висцеральных проявлений псориатической болезни. Врач, дело 1988; 8; 88-91.
  6. Бадокин В. В. Особенности течения злокачественной формы псориатического артрита. Врач 1999; 5; 23-25.
  7. Reed W. В., Becker S. W., Russel R., Heiskell C. L. Psoriasis and arthritis. Arch. Deratol. 1961; 83 (4): 541-548.
  8. Белова Е. В., Бургунская Е. А., Кактурский Л. В. и др. Клинико-морфологические проявления поражения сердца при псориазе. Кардиология 1995; 5: 62-66.
  9. Cosh J. A., Lever J. V. Rheumatic diseases and the heart. London; 1988. 165-192.
  10. Buslau M., Benotmane K. Cardiovascular complications of psoriasis does obstructive sleep apnoe play a role? Acta Dermatol. Venereol. 1999; 79 (3): 234.
  11. Fukuhara K., Urano Y. A., Akaike M., Arose S. Psoriatic arthritis with dilated cardiomyopathy and Takayasu's arteritis. Br. J. Dermatol. 1998; 138: 329-333.
  12. Rowe I. E, Gibson D. G, Keat A. C., Brewerton D. A. Echocardiographic diastolic abnormalities of the left ventricle in inflammatory joint disease. Ann. Rheum. Dis. 1991; 50 (4): 227-230.
  13. Svistunov I. V., Shlopov I. G., Shevchenko T. I. The hearts morphological changes in psoriasis. In: 6-th International psoriasis symposium. Chicago; 1994. 17-19.
  14. Sanchez M. Psoriatic arthritis with aortic insufficiency and complete atrioventricular blockade. Rev. Esp. Cardiol. 1989; 42 (1): 68-70.
  15. Todoroki Т., Tsukamuto H., Matsumoto К., Капо S. A case of proriatic arthritis complicated by iridocyclitis, pericarditis and atlanto-axial subluxation. Ryumachi 1981; 21 (5): 407-413.
  16. Ujfalussy I., Kempler P., Koo E., Seszlac M. Cardiac abnormalities in psoriatic arthritis. In: 12-th European congress of rheumtology: Abstracts. Budapest; 1991. FP 9-94.
  17. Коршунов H. И., Дормидонтов E. H., Джурко Е. Ю. Клинико-эхокардиографическая характеристика поражения сердца при серонегативных спондилоартритах (болезни Рейтера, болезни Бехтерева, псориатическом артрите). Тер. арх. 1991; 5: 41-45.
  18. Michet С. J. Psoriatic arthritis. In: Kelly W. N., Harris E. D., Ruddy S., Sledge С. В., eds. Textbook of rheumatology. Philadelphia: W. B. Saunders Company; 1993. 974-984.
  19. Muna W. F., Roller D. H., Craft J. Psoriatic arthritis and aortic regurgitation. J. A. M. A. 1980; 244: 363-365.
  20. Torre-Alonso J. C., Rodrigues Perez A., Arribas Castrillo J. M. et al. Psoriatic arthritis: a clinical, immunological and radiological study of 180 patients. Br. J. Rheumatol. 1991; 30: 245- 250.
  21. Pines A., Ehenfeld M., Fisman E. Z. et al. Mitral valve prolapse in psoriatic arthritis. Arch. Intern. Med. 1986; 146 (7): 1371- 1373.
  22. Khan M. A. Ankylosing spondylitis: clinical aspects. In: Calin A., Taurog J. Т., eds. Spondylarthrites. Oxford: Oxford University Press; 1998. 1-15.

Statistics

Views

Abstract - 117

Cited-By


Article Metrics

Metrics Loading ...

Refbacks

  • There are currently no refbacks.

Copyright (c) 2020 Badokin V.V., Kotelnikova G.P.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
 

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Novoslobodskaya str 31c4., Moscow, 127005, Russian Federation

Managing Editor:

 

© 2018 "Consilium Medicum" Publishing house


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies