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Ethnic differences in apolipoprotein В levels in hyperlipidemia in Russians and the Kirghiz
- Authors: Mirrakhimov EM1, Noruzbaeva AM1, Lunegova OS1, Afanasyeva MI1, Adamova IY.1, Pokrovsky SN1, Poroschai EN1, Mirrakhimov MM1
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- Issue: Vol 79, No 6 (2004)
- Pages: 35-39
- Section: Editorial
- URL: https://ter-arkhiv.ru/0040-3660/article/view/29827
- ID: 29827
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Abstract
Material and methods. Lipid spectrum of the blood (LDLP and HDLP cholesterol, total cholesterol, triglicerides), apo-B, CHD risk factors were studied in 60 Russian and 75 Kirghis patients with PHL aged 28 to 67years (mean age 50.0 + 7.59 years, 56females and 79 males). Results. In Russians a mean level of LDLP cholesterol and apo-B was significantly higher than in Kirghiz patients (3.95 + 1.29 mmol/l vs 3.51+1.17 mmol/l, p = 0.042; 173.3+ 57.3 mg/dl vs 145.5 + 49.3 mg/dl, p = 0.003, respectively). CHD in both ethnic groups occurred with similar rates. The multifactorial regression analysis shows that an apo-B concentration can serve an independent risk factor associated with CHD in the Kirghiz population (p = 0.25, p = 0.03) while in Russians living in Kirghizia this factor is a low content of HDLP cholesterol (p = -0.25, p = 0.05).
About the authors
E M Mirrakhimov
A M Noruzbaeva
O S Lunegova
M I Afanasyeva
I Yu Adamova
S N Pokrovsky
E N Poroschai
M M Mirrakhimov
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