Videothoracoscopic collagen pleurodesis in malignant pleural exudate


Cite item

Full Text

Abstract

Aim. To devise the technique and evaluate the efficacy of videothoracoscopic collagen pleurodesis (VCP) in malignant pleural exudates (MPE).
Material and methods. VCP was performed in 24 patients with recurrent MPE. 20 patients were diagnosed to have non-small-cell cancer of the lung, 4 patients - breast cancer. The operation included videothoracoscopic revision of the pleural cavity under endobronchial anesthesia, pleural biopsy, liquid evacuation, dispersion of powder collagen (1 g) and drainage of the pleural cavity. Results. Videothoracoscopy macroscopically diagnoses pleural carcinomatosis in 100% patients. Pathomorphological examination of the biopsies defined a histological type of the tumor in all 24 patients. A positive clinicoroentgenological effect with a compete disappearance of pleural exudates was achieved in all the cases. The recurrence was absent in 18 of 24 patients. Short- and long-term results, survival and quality of life are outlined.
Conclusion. VCP is a simple and effective method of palliative treatment improving quality of life in patients with malignant pleural exudates.

References

  1. Sahn S. A. Malignancy metastatic to the pleura. Clin. Chest Med. 1998; 19: 351-361.
  2. Чучалин А. Г. Плевра: патофизиологические и клинические аспекты. Пульмонология 1999; 1: 6-10.
  3. Акопов А. Л., Кондратьев В. Б. Лечение метастатических опухолевых экссудативных плевритов внутри полостным введением блеомицетина. Вопр. онкол. 1999; 4: 411-415.
  4. Aelony Y., King R., Boutin С. Thoracoscopic talc poudrage for chronic recurent pleural effusion. Ann. Intern. Med. 1991; 115: 778-782.
  5. Danby C. A., Adebonojo S. A., Moritz D. M. Video-assisted talc pleurodesis for malignant pleural effusions utilizing local anethesia and L. V. sedation. Chest 1998; 113: 739-742.
  6. Vargas F. S., Teixeira L. R. Pleural malignancies. Curr. Opin. Pulm. Med. 1996; 2: 335-340.
  7. Варламов В. В. Эмфизема легких (патогенез, дтагностика и хирургическое лечение): Автореф. дис. ... д-ра мед. наук. Л.; 1991.
  8. Хилькин А. М., Шехтер А. Б., Истранов Л. П., Лемеиев В. Л. Коллаген и его применение в медицине. М.: Медицина; 1976.
  9. Karnofsky D. A., Burchenal V. H. The clinical evaluation of chemotherapeutic agents in cancer. In: MacLeod С. М., cds. Evaluation of chemotherapeutic agents. New York: Columbia University Press; 1949. 191-205.
  10. Webb W. R., Ozmen V., Moulder P. V. et al. Iodized talk pleurodesis for the treatment of pleural effusions. J. Thorac. Cardiovasc. Surg. 1992; 103: 881-886.
  11. Jancovici R., Lang-Lazdunski L., Pons F., Cador L. Complications of video-assisted thoracic surgery: a five-year experience. Ann. Thorac. Surg. 1996; 61: 533-537.
  12. Sahn S. A., Good T. Pleural fluid pH in malignant effusions: Diagnostic, prognostic and therapeutic implications. Ann. Intern. Med. 1988; 108: 345-350.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2004 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
 

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Managing Editor:

  • Tel.: +7 (926) 905-41-26
  • E-mail: e.gorbacheva@ter-arkhiv.ru

 

© 2018-2021 "Consilium Medicum" Publishing house


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies