Diagnostic and prognostic significance of D-dimer in internal medicine

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  1. Shainoff J. R., DiBello P. M. The circulatory half-lives of aprofibrin and a-fibrin monomer, and comparisions with other fibrin(ogen) derivatives. Thromb. and Haemost. 2003; 89: 48- 52.
  2. Dempfle C.-E., Zips S., Ergiil H. et al. The fibrin assay comparison trial (FACT): Correlation of soluble fibrin assays with Ddimer. Ibid. 2001; 86: 1204-1209.
  3. Brummel K. E., Butenas S., Mann K. G. An integral study of fibrinogen during blood coagulation. J. Biol. Chem. 1999; 274: 22862-22870.
  4. Dempfle C.-E., Zips S., Ergiil H. et al. The fibrin assay comparison trial (FACT): Evaluation of 23 quantitative D-dimer assays as basis for the development of D-dimer calibrators. Thromb. and Haemost. 2001; 85: 671-678.
  5. Wells P. S., Brill-Edwards P., Stewenson P. et al. A novel and rapid whole-blood assay for D-dimer in patients with clinically suspected deep vein thrombosis. Circulation 1995; 91: 2184- 2187.
  6. Vissac A. M., Grimaux M., Chartier S. et al. A new sensitive membrane based ELISA technique for instantaneous D-dimer evaluations in emergency. Thromb. Res. 1995; 78: 341-352.
  7. Pittet J. L., Moerloose P., Reber G. et al. VIDAS D-dimer: fast quantitative ELISA for measuring D-dimer in plasma. Clin. Chem. 1996; 42: 410-415.
  8. Hubbuch A., Adema E., Gebert U., Herz R. Multicentre evaluation of Tina-quant U D-dimer, a latex based reagent for BM/ Hitachi systems. Klin. Lab. 1995; 41: 383-386.
  9. Tataru M., Heinrich J. D-dimer in relation to the severity of arteriosclerosis in patients with stable angina pectoris after myocardial infarction. Eur. Heart J. 1999; 20: 1493-1502.
  10. Merlini P. A., Ardissino D. Current status of coagulation markers in ischemic heart disease: Markers of coagulation activa tion. Thromb. and Haemost. 1997; 78: 276-279.
  11. Ridker P. M. Fibrinolytic and infammatory markers for arterial occusion: The evolving epidemiology of thrombosis and he mostasis. Ibid. 53-59.
  12. Tripodi A., Mannucci P. M. Markers of activated coagulation and their usefulness in the clinical laboratory. Clin. Chem. 1996; 42: 664-669.
  13. Ridker P. M., Hennekens С. Н., Cerskus A. et al. Plasma concentration of crosslinked fibrin degradation product (D-dimer) and risk of future myocardial infarction among apparently healthy men. Circulation 1995; 90: 2236-2240.
  14. Lowe G. D. O., Rumley A., Yarnell J. W. G. et al. Fibrin Ddimer, von Willebrand factor and tissue plasminogen activator antigen are predictors of major ishemic heart disease: the Caerthilly study. Blood Coagul. Fibrinolys. 1995; 6: 156-157.
  15. Folsom A., Wu K., Rosamond W. Prospective study of hemostatic factors and incidence of coronary heart disease: The atherosclerosis risk in communities (ARIC) study. Circulation 1997; 96: 1102-1108.
  16. Lee V. L., Ewald G. A., McKenzie C. R. et al. The relatonship of soluble fibfin and cross-linked fibrin degradation products to the clinical course of myocardial infarction. Arterioscler. Thromb. Vase. Biol. 1997; 17: 628-633.
  17. Fowkes F. G. R., Lowe G. D. O., Housley E. Cross-linked fibrin degradation products, progression of peripheral artetial disease, and risk of coronary heart disease. Lancet 1993; 342: 84-86.
  18. Комаров А. Л. Д-димер и функция тромбоцитов как предикторы тромботических осложнений у больных с атеросклеротическим поражением артерий нижних конечностей (результаты 5-летнего наблюдения). Кардиология 2000; 9: 16-22.
  19. Nicoladies A. N., Bergqvist D., Hull R. Prevention of venous thromboembolism. International consensus statement. Intern. Angiol. 1997; 16: 3-38.
  20. Панченко Е. П., Добровольский А. Б. Тромбозы в кардиологии. Механизмы развития и возможности терапии. М.: Спорт и культура; 1999.
  21. Eisenberg P. R. Does a negative D-dimer exclude thrombosis? Fibrinolysis 1993; 7 (suppl. 2): 32-35.
  22. Bounameaux H., Scheider P. A., Reber G. et al. Measurement of plasma D-dimer for diagnosis of deep venous thrombosis.Am. J. Pathol. 1989; 91: 82-85.
  23. Tengborn L., Palmblad S., Wojciechowski J. D-dimer and thrombin/antithrombin III eomplex-diagnostic tools in deep vein thrombosis? Haemostasis 1994; 24: 344-350.
  24. Dale S., Gostad G. O., Brosstad F. et al. Comparison of three Ddimer assays for the diagnosis of DVT: ELISA, latex and immunofiltration assay (NycoCard Ddimer). Thromb. and Haemost. 1994; 71: 270-274.
  25. Hansson P. O., Eriksson H., Eriksson E. et al. Can laboratory testing improve screening strategies for deep vein thrombosis at an emergency unit? J. Intern. Med. 1994; 235: 143-151.
  26. Chang-Liem G. S., Lustermans F. А. Т., van Wersch J. W. J. Comparison of the approaches of latex and ELISA D-dimer determination for the diagnosis of deep vien thrombosis. Haemostasis 1991; 21: 106-110.
  27. Ginsberg J. S., Kearson C, Douketis J. et al. The use Ddimer testing and impedance plethysmographic examination in patients with clinical indications of deep vein thrombosis. Arch. Intern. Med. 1997; 157: 1077-1081.
  28. Bernardi E., Prandoni P., tensing A. W. et al. D-dimer testing as an adjunct to ultrasonography in patients with clinically suspected deep vein thrombosis: prospective cohort study. The Multicentre Italian D-dimer Ultrasound Study Investigators Group. Br. Med. J. 1998; 317: 1037-1040.
  29. Ginsberg J. S., Wells P. S., Kearson C. et al. Sensitivity and specificity of rapid whole-blood assay for D-dimer in the diagnosis of pulmonary embolism. Ann. Intern. Med. 1998; 129: 1006-1011.
  30. Perrier A., Bounameaux H., Morabia A. et al. Diagnosis of pulmonary embolism by a decision analysis-based strategy including clinical probability, D-dimer levels, and ultrasonography: a management study. Arch. Intern. Med. 1996; 156: 531-536.
  31. Palareti G, Legnani C, Cosmi B. et al. Risk of venous thromboembolism recurrence: high negative predictive value of Ddimer performed after oral anticoagulation is stopped. Thromb. and Haemost. 2002; 87: 7-12.
  32. Nordstrom M., Lindblad В., Anderson H. et al. Deep venous thrombosis and occult malignancy: an epidemiological study.Br. Med. I. 1994; 308: 891-894.
  33. Mac Lennan A. Outpatient D-dimer test can exclude deep ve nous thrombosis. Am. J. Med. 2002; 112 (8): 617-621.
  34. Kierkegaard A. Incidence and diagnosis of deep vein thrombosis associated with pregnancy. Acta Obstet. Gynecol. Scand. 1983; 62: 239-243.
  35. Treffers P. E., Huidekoper B. L., Weenink G. H. et al. Epidemiological observations of thromboembolic disease during pregnancy and in the puerperium, in 56,022 women. Int. J. Gynaecol. Obstet. 1983; 21: 327-331.
  36. Conard J., Horellou M. H., Van Dreden P. Thrombosis and pregnancy in congenital dificiencies in ATIII, protein С or S: study of 78 women. Thromb. and Haemost. 1990; 63: 319- 320.
  37. Long A., Ginsberg J., Brill-Edwards P., Johnston M. The relationship of antiphospholipid antibodies to thromboembolic disease in systemic lupus erythematosus: a cross-sectional study. Ibid. 1991; 66: 520-524.
  38. Папаян Л., Князева Е. Д-димер в клинической практике: Пособие для врачей. М.; 2002.
  39. Mondillo S., Sabatini L., Agricola E. et al. Correlation between left atrial size, prothrombotic state and markers of endotelian dysfunction in patients with lone chronic nonrheumatic atrial fibrillation. Int. J. Cardiol. 2000; 75 (2-3): 227-232.
  40. Roldan V., Marin F., Marco P. et al. Hypofibrinolysis in atrial fibrillation. Am. Heart J. 1998; 16 (6): 956-960.
  41. Mitusch R., Siemens H. J., Garbe M. et al. Detection of a hypercoagulable state in nonvalvular atrial fibrillation and the effect of anticoagulant therapy. Thromb. and Haemost. 1996; 75: 219-223.
  42. Nakajima K. The relationship between left atrial thrombus and hematological markers in patients with chronic non-rheumatic atrial fibrillation. Nippon Ronen Igakkai Zasshi 2000; 37 (11): 903-907.
  43. Lip G. Y. N., Rumley A., Dunn F. G. et al. Plasma fibrinogen and fibrin D-dimer levels in patients with AF: effects of cardioversion to sinus rhythm. Int. J. Cardiol. 1995; 51: 245-253.
  44. The DYTENOX Study b Group. Markers of hemostatic system activation in acute deep venous thrombosis - evolution during the first days of heparin treatment. Thromb. and Haemost. 1993; 70:909-914.
  45. Elias A., Bonflls S., Daoud-Elias M. et al. lnfuence of long oral anticoagulants upon prothrombin fragment 1+2, thrombin-antithrombin III complex and D-dimer levels in patients affected by proximal deep vein thrombosis. Ibid. 69: 302-305.
  46. Roldan V., Marin F., Marco P. et al. Anticoagulant therapy modifies fibrinolytic dysfunction in chronic atrial fibrillation. Haemostasis 2000; 30 (4): 219-224.

Copyright (c) 2003 Fedotkina Y.A., Dobrovobky А.В., Kropacheva E.S., Titaeva E.V., Panchenko E.P.

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