Alcohol consumption and its link withcardiovascular mortality in 40-59 year old males (data of a21.5 year prospective study)

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Aim. To study contribution of alcohol consumption (AC) to mortality of coronary heart disease
(CHD), cerebral stroke (CS), cardiovascular diseases (CVD), overall mortality (OM) in a random
population of working males.
Material and methods. The results are available of a 21.5 year cohort study of mortality in a random
population of 7815 male citizens of Moscow and St-Petersburg aged 40-59 years.
Results. The attributive risk of AC for mortality of CHD, CS, CVD and ОМ was 16.6, 14.8, 7.7and
11.9%, respectively. The lowest relative risk to die of CHD, CVD and OM among the cohort studied
was observed in males taking alcohol 168.0 ml per week maximum.
Conclusion. It is necessary to approach differentially to assessment of AC effects on development of
many diseases and further investigations are needed to reveal fine mechanisms of action of different
alcohol drinks on human organism.


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