New approaches in the tomographic visualization of joints using X-ray contrast nanoparticles and laser radiation

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

New approaches in X-ray visualization of joints using various radiation sources are considered. Investigations of the structure of joint cartilage tissue and model objects structurally and functionally similar to cartilage tissue were conducted using X-ray radiation from a laboratory microtomograph and synchrotron radiation. Images of the internal structure of model objects and cartilage tissue impregnated with X-ray contrast agent were obtained using projection radiography and microtomography methods. Colloidal solutions of biocompatible nanoparticles of titanium and molybdenum oxides were used as contrasting agents. The nanoparticle concentration distribution through tissue depth was measured by image processing.

Толық мәтін

Рұқсат жабық

Авторлар туралы

A. Omelchenko

Shubnikov Institute of Crystallography of Kurchatov Complex of Crystallography and Photonics of NRC “Kurchatov Institute”

Хат алмасуға жауапты Автор.
Email: sig74@mail.ru
Ресей, Moscow

I. Dyachkova

Shubnikov Institute of Crystallography of Kurchatov Complex of Crystallography and Photonics of NRC “Kurchatov Institute”

Email: sig74@mail.ru
Ресей, Moscow

D. Zolotov

Shubnikov Institute of Crystallography of Kurchatov Complex of Crystallography and Photonics of NRC “Kurchatov Institute”

Email: sig74@mail.ru
Ресей, Moscow

A. Kaloyan

Shubnikov Institute of Crystallography of Kurchatov Complex of Crystallography and Photonics of NRC “Kurchatov Institute”

Email: sig74@mail.ru
Ресей, Moscow

V. Shepeleva

Shubnikov Institute of Crystallography of Kurchatov Complex of Crystallography and Photonics of NRC “Kurchatov Institute”

Email: sig74@mail.ru
Ресей, Moscow

K. Podurets

Shubnikov Institute of Crystallography of Kurchatov Complex of Crystallography and Photonics of NRC “Kurchatov Institute”

Email: sig74@mail.ru
Ресей, Moscow

Әдебиет тізімі

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Әрекет
1. JATS XML
2. Fig. 1. The scheme of the experiment on radiography of biological samples on a beam of SI. The callouts indicate the distances from the SI source to the installation site

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3. Fig. 2. Diagram of an X–ray microtomograph: 1 – X–ray source (X–ray tube), 2 – monochromator unit, 3 – vacuum path (collimator), 4 - vacuum pump, 5 - sample under study and positioning system, 6 - X-ray detector XIMEA xiRAY11, 7 – local radiation protection zone

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4. Fig. 3. X-ray images of model samples (a, b) and cartilage tissue (c) obtained using SI at photon energy E = 25 keV (arrows indicate particle agglomerates)

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5. Fig. 4. Distribution of radiopaque nanoparticles Na0.2TiO2 by cartilage depth

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6. Fig. 5. Results of three–dimensional reconstruction of a sample of articular cartilage isolated from the epiphysis of the tibia of a cow with Na0.2TiO2 nanoparticles: a - the entire sample, b – areas for an enlarged image are highlighted, c, d – tomography of the lower and upper fragments highlighted in Fig. b, respectively, e, f – after the segmentation procedure the entire volume and surface layer, g – lateral tomographic projection (visualization of the applied layer)

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7. Fig. 6. View of the cartilaginous plate on the joint bone (sagittal incision)

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