EFFECTIVE SYNTHESIS OF OPTICALLY PURE MONO- AND BINUCULAR MACROCYCLIC POLYLACTONES FROM CASTOR OIL AND SEBACIC ACID

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An effective synthesis of optically pure macrocyclic mono- and dinuclearpolylactones is proposed, based on the condensation of a natural triol – castor oil with sebacic acid dichloride, taken in ratios 1 : 1 or 1 : 2, in boiling carbon tetrachloride in the presence of triethylamine and the catalyst N,N-dimethylaminopyridine.

作者简介

G. Ishmuratov

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

Email: insect@anrb.ru
Russian Federation, 450054, Ufa

N. Medvedeva

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

Email: insect@anrb.ru
Russian Federation, 450054, Ufa

K. Saitov

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

Email: insect@anrb.ru
Russian Federation, 450054, Ufa

M. Yakovleva

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

编辑信件的主要联系方式.
Email: insect@anrb.ru
Russian Federation, 450054, Ufa

I. Nazarov

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

Email: insect@anrb.ru
Russian Federation, 450054, Ufa

A. Tolstikov

Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences

Email: insect@anrb.ru
Russian Federation, 450054, Ufa

参考

  1. Ишмуратов Г.Ю., Яковлева М.П., Выдрина В.А., Денисова К.С., Саяхов Р.Р., Вильданова Р.Р., Вырыпаев Е.М., Толстиков А.Г. // Химия природ. соед. 2017. № 4. С. 528–530. https://doi.org/10.1007/s10600-017-2073-5
  2. Мингалеева Г.Р., Яковлева М.П., Денисова К.С., Ишмуратов Г.Ю. // Макрогетероциклы. 2020. Т. 13. № 1. С. 79–82. https://doi.org/10.6060/mhc190661m
  3. Sailakshmi G., Mitra T., Gnanamani A. // Prog. Biomat. 2013. V. 2. P. 11. https://doi.org/10.1186/2194-0517-2-11
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  5. Mingrone G., Castagneto-Gissey L., Macé K. // Br. J. Clin. Pharmacol. 2013. V. 75. № 3. P. 671–676. https://doi.org/10.1111/j.1365-2125.2012.04177.x
  6. Niewolik D., Bednarczyk-Cwynar B., Ruszkowski P., Jaszcz K. // Proceedings. 2020. V. 67. № 1. P. 17 (1–6). https://doi.org/10.3390/ASEC2020-07558
  7. Выдрина В.А., Саяхов Р.Р., Яковлева М.П., Зилеева З.Р., Талипов Р.Ф., Ишмуратов Г.Ю. // Химия природ. соедин. 2021. № 4. С. 603–607. https://doi.org/10.1007/s10600-021-03454-3

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版权所有 © Г.Ю. Ишмуратов, Н.И. Медведева, К.М. Саитов, М.П. Яковлева, И.С. Назаров, А.Г. Толстиков, 2023