电邮这篇文章 In vitro and in vivo biodegradation of silk fabric scaffolds
- 作者: Agapov I.I.1, Podbolotova E.I.1,2, Nemets E.A.1, Kirsanova L.A.1, Grudinin N.V.1, Pashutin A.R.1,2, Agapova O.I.1, Efimov A.E.1, Basok Y.B.1, Lyundup A.V.3, Gautier S.V.1,4
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隶属关系:
- Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
- Moscow Institute of Physics and Technology
- Рeoples’ Friendship University of Russia
- Sechenov University
- 期: 卷 520, 编号 1 (2025)
- 页面: 45-49
- 栏目: Articles
- URL: https://ter-arkhiv.ru/2686-7389/article/view/682031
- DOI: https://doi.org/10.31857/S2686738925010089
- EDN: https://elibrary.ru/tcqqzj
- ID: 682031
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详细
This study investigates the biodegradation of natural silk scaffolds made from gauze and satin fabrics under in vitro and in vivo conditions. Experiments were conducted using phosphate-buffered saline and Fenton’s reagent to model degradation. The samples demonstrated high stability under physiological conditions’ model and exhibited varying degradation rates under oxidative stress. In vivo studies on rats revealed good biocompatibility of the scaffolds and a gradual reduction in inflammatory responses. These findings highlight the potential of silk scaffolds for use in various areas of regenerative medicine.
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作者简介
I. Agapov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow
E. Podbolotova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation; Moscow Institute of Physics and Technology
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow; Dolgoprudny
E. Nemets
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow
L. Kirsanova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow
N. Grudinin
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow
A. Pashutin
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation; Moscow Institute of Physics and Technology
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow; Dolgoprudny
O. Agapova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow
A. Efimov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow
Yu. Basok
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow
A. Lyundup
Рeoples’ Friendship University of Russia
Email: igor.agapov@gmail.com
俄罗斯联邦, Moscow
S. Gautier
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of the Russian Federation; Sechenov University
Email: igor.agapov@gmail.com
Academician of the RAS
俄罗斯联邦, Moscow; Moscow参考
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