WHAT TREATMENT REGIMENS FOR HELICOBACTER PYLORI INFECTION ARE NECESSARY TODAY?


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Abstract

Triple first-line therapy, despite its inefficiencies due to growing resistance to clarithromycin and metronidazole, remains the therapy of choice for primary treatment of patients with Helicobacter pylori infection. One of the ways to increase efficiency of the 7-day first-line regimens with clarithromyc is the use of modern and more effective proton pump inhibitors (PPIs) such as esomeprazole, providing 5-10% advantage over the first-generation PPIs (nonisomers). As a salvage therapy in Russia, sequential (standard or modified) therapy, schemes with amoxicillin, bismuth preparations, and furazolidone can be used, if it is regulated by national guidelines.

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