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Potential use of Acrocomia aculeata Pulp Oil in the Modulation of Chronic Non-communicable Diseases, Especially in Diabetes: A Systematic Review

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1. Title Title of document Potential use of Acrocomia aculeata Pulp Oil in the Modulation of Chronic Non-communicable Diseases, Especially in Diabetes: A Systematic Review
2. Creator Author's name, affiliation, country Maurílio de Souza Cazarim; Department of Pharmaceutical Sciences, School of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Brazil
2. Creator Author's name, affiliation, country Davi Aleixo; Department of Pharmaceutical Sciences, School of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Brazil
2. Creator Author's name, affiliation, country Estael da Cruz-Cazarim; Department of Pharmaceutical Sciences, School of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Brazil
2. Creator Author's name, affiliation, country Mohamed Abd El-Salam; Department of Pharmacognosy, Faculty of Pharmacy, Delta University for Science and Technology International
Coastal Road, Gamasa, Egypt; Department of Medicine, Harvard Medical School, Boston, USA; Department of Medicine,
VA Boston Healthcare System, Boston, USA
2. Creator Author's name, affiliation, country Frederico Pittella; Department of Pharmaceutical Sciences, School of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Brazil
3. Subject Discipline(s)
3. Subject Keyword(s) Non-communicable diseases; biological products; drug evaluation; preclinical; pharmaceutical preparations; diabetes mellitus; glycemic control.
4. Description Abstract

Introduction:The fruit oil from Acrocomia aculeata (Macauba or Bocaiuva) is highly rich in antioxidants and other bioactive compounds, emerging as a natural source of high potential for the modulation of chronic non-communicable diseases (NCDs), like diabetes. Its effects on chronic NCDs are poorly studied yet. Our review aimed to evaluate the therapeutic results of pharmaceutical preparations containing Acrocomia aculeata pulp oil that are used for chronic NCDs.

Method:A search was performed using PICO acronyms in English, Portuguese, and Spanish languages in the MEDLINE®, PubMed, EMBASE, Scopus, LILACs, and CENTRAL Cochrane Library databases. The degree of agreement for selection and eligibility was significant (Kappa= 0.992; 95% CI: 0.988-0.996). The difference between the intervention and control groups for blood glucose reduction was 63.5 ± 69.5 mg/dL (p(<0.0001).

Result:Overall, an improvement percentage of 55.1 ± 0.1 was observed for the variables associated with chronic NCDs, which represented 89.96% of the relative risk reduction (efficacy).

Conclusion:The Acrocomia aculeate pulp oil exhibited promising results in experimental studies for glycemic control and reduction of a specific tumor, indicating a good potential to be explored for chronic NCDs treatment.

5. Publisher Organizing agency, location Bentham Science
6. Contributor Sponsor(s)
7. Date (DD-MM-YYYY) 01.05.2024
8. Type Status & genre Peer-reviewed Article
8. Type Type Research Article
9. Format File format
10. Identifier Uniform Resource Identifier https://ter-arkhiv.ru/1573-3998/article/view/643001
10. Identifier Digital Object Identifier (DOI) 10.2174/1573399820666230913105935
11. Source Title; vol., no. (year) Current Diabetes Reviews; Vol 20, No 5 (2024)
12. Language English=en
13. Relation Supp. Files
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
15. Rights Copyright and permissions Copyright (c) 2024 Bentham Science Publishers