Email this article Diagnosis of tuberculous pericarditis in patients with HIV-infection
- Authors: Toshchevikov M.V.1, Zimina V.N.1, Batyrov F.A.1, Kravchenko A.V.1, Vasil'eva I.A.1, Toschevikov MV2, Zimina VN3, Batyrov FA2, Kravchenko AV4, Vasilieva IA3
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Affiliations:
- Tuberculosis hospital N 7, Moscow
- Central Research Institute of Tuberculosis, Moscow
- Central Research Institute of Epidemiology, Moscow
- Issue: Vol 83, No 11 (2011)
- Pages: 14-19
- Section: Editorial
- URL: https://ter-arkhiv.ru/0040-3660/article/view/30913
- ID: 30913
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Abstract
Material and methods. We analysed results of diagnosis of 304 primary patients with organ tuberculosis in combination with HIV infection treated in Moscow tuberculosis hospital N 7 in 2006-2010. CD4 lymphocyte count median in tuberculosis onset was 140 in 1 mcl, 63.2% patients had a baseline level of CD4 lymphocytes under 200 in 1 mcl.
Results. TP incidence in primary patients with tuberculosis and HIV-infection was 6.3% while in patients with tuberculosis of multiple locations - 13.7%. Cardiac tamponade symptoms were registered only in one case. Pericardial effusion was classified as moderate and large in 68.4% patients. Patients with large effusion (more than 20 mm in isolation of pericardial leaves) have undergone diagnostic pericardiocentesis and, in some cases, microdrainage. Sensitivity of exudate test for M. tuberculosis DNA with use of polymerase chain reaction was 100%.
Conclusion. Active surgical policy in massive effusion tuberculosis pericarditis in line with adequate antituberculosis and antiretrovirus therapy in HIV-infecterd patients results in rapid resorption of the effusion.
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About the authors
Mikhail Vasil'evich Toshchevikov
Email: tkb7@mosgorzdrav.ru
Vera Nikolaevna Zimina
Email: vera-zim@yandex.ru
Farit Akhatovich Batyrov
Email: tkb7@mosgorzdrav.ru
Aleksey Viktorovich Kravchenko
Email: kravtchenko@hivrussia.net
Irina Anatol'evna Vasil'eva
Email: vasil39@list.ru
M V Toschevikov
Tuberculosis hospital N 7, MoscowTuberculosis hospital N 7, Moscow
V N Zimina
Central Research Institute of Tuberculosis, MoscowCentral Research Institute of Tuberculosis, Moscow
F A Batyrov
Tuberculosis hospital N 7, MoscowTuberculosis hospital N 7, Moscow
A V Kravchenko
Central Research Institute of Epidemiology, MoscowCentral Research Institute of Epidemiology, Moscow
I A Vasilieva
Central Research Institute of Tuberculosis, MoscowCentral Research Institute of Tuberculosis, Moscow
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