Different characteristics of quality of life in celiac disease patients


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Aim. To study quality of life (QoL) in patients with celiac disease (CD) in the course of treatment with aglutenic diet (AD).
Material and methods. Modern algorithm of glutenic enteropathy diagnosis (enzyme immunoassay, histological examination of the biopsy of distal duodenum mucosa) was used in 650 patients with different gastrointestinal symptoms. QoL was assessed in the course of AD treatment of CD with application of universal standard questionnaire MOS SF-36.
Results. CD was diagnosed in 56 (8.6%) patients. Classic CD was diagnosed in 44 (78.6%) patients, atypical CD - in 12 (21.4%). Significant lowering of QoL characteristic "psychological health" was observed in CD patients under 30 and over 50 and "physical health" in 30-50-year-old CD patients. Women had low points on "mental health" scale. After 3 AD months QoL worsened by all the scales, but after 12 months QoL significantly improved.
Conclusion. QoL in patients with classic CD is associated with gender and age. First, AD deteriorates QoL, but 1-year diet therapy improves QoL.

作者简介

Elena Moiseenko

Marina Osipenko

Email: ngma@ngs.ru

Tat'yana Ageeva

Sergey Krotov

Email: krotov@vector-best.ru

N Burbik

Email: burbik@vector-best.ru

E Moiseenko

State Medical University, Novosibirsk

State Medical University, Novosibirsk

M Osipenko

State Medical University, Novosibirsk

State Medical University, Novosibirsk

T Ageeva

State Medical University, Novosibirsk

State Medical University, Novosibirsk

S Krotov

Vektor-Best Corporation, Novosibirsk

Vektor-Best Corporation, Novosibirsk

N Burbik

Vektor-Best Corporation, Novosibirsk

Vektor-Best Corporation, Novosibirsk

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