Population association features of interleukine gene polymorphism in khakases with gastroduodenal diseases


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Abstract

Aim. To investigate association of polymorphisms of IL-1 genes and antagonist of IL-2 receptor (IL1Ra).
Material and methods. Patients with chronic gastritis and ulcer were examined using the method of restriction analysis.
Results. It was found that CCIL1beta and R4/R4IL1Ra are most prevalent allel variants in khakas population.
Conclusion. It is expedient to define population risk and protective genotypes of development of ulcer associated with Helicobacter pylori in khakases.

About the authors

Elizaveta Sergeevna Ageeva

Email: Ageevaeliz@rambler.ru

Ol'ga Vladimirovna Shtygasheva

Email: olgashtygasheva@rambler.ru

Natal'ya Vladimirovna Ryazantseva

Email: nv_ ryazan@mail.ru

E S Ageeva

N.F. Katanov Khakas State University, Abakan

N.F. Katanov Khakas State University, Abakan

O V Shtygasheva

N.F. Katanov Khakas State University, Abakan

N.F. Katanov Khakas State University, Abakan

N V Ryazantseva

Siberian State Medical University, Tomsk

Siberian State Medical University, Tomsk

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