Risk factors for venous thromboembolic events and their association with D-dimer level
- 作者: Vorobyeva NM1, Panchenko EP1, Dobrovolsky AB1, Titayeva EV1, Fedotkina Y.A1, Kiriyenko AI2
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隶属关系:
- Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
- N. I. Pirogov Russian State Medical University, Moscow
- 期: 卷 82, 编号 8 (2010)
- 页面: 30-34
- 栏目: Editorial
- ##submission.dateSubmitted##: 09.04.2020
- ##submission.datePublished##: 15.08.2010
- URL: https://ter-arkhiv.ru/0040-3660/article/view/30626
- ID: 30626
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Subjects and methods. The clinical, demographic, anthropometric, anamnestic, and laboratory data were analyzed in 106 patients (73 men and 33 women) aged 18 to 78 years admitted to hospital with the first or recurrent episode of VTEE.
Results. RF and VTEE-associated diseases were identified in all patients. Over 90% of the patients had more 2 RFs. The most common RFs were the age above 40 years (85%) and overweight (82%), including obesity (42%). There was a preponderance of cardiovascular diseases in the pattern of VTEE-associated diseases. The direct causes (precipitating factors) of thrombosis were revealed in 57% of cases; the thrombotic episode was classified as idiopathic in 43%. Elevated D-dimer levels were found in 74% of the patients. Higher D-dimer content was seen in women, non-smokers, patients operated on for thrombosis, those who had 2 precipitating factors or more, and those who had a less than 30-day history of thrombosis. There was an inverse correlation between the elevated level of D-dimer and the duration of thrombosis by the moment of its identification (thrombus age).
Conclusion. All patients who have experienced a venous thrombotic episode have various RFs for VTEE. The content of D-dimer exceeds the normal value in most patients with VTEE. Among the RFs studied, thrombus age is the most important factor associated with elevated D-dimer levels in patients with VTEE.
作者简介
N Vorobyeva
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
Email: natalyavorobjeva@mail.ru
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
E Panchenko
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
Email: lizapanchenko@mail.ru
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
A Dobrovolsky
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
Email: abdobrovolsky@inbox.ru
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
E Titayeva
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
Email: evlti@mail.ru
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
Yu Fedotkina
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
Email: yu_fedotkina@mail.ru
Russian Cardiology Research-and-Production Complex, Russian Agency for Medical Technologies, Moscow
A Kiriyenko
N. I. Pirogov Russian State Medical University, Moscow
Email: phlebo-union@mtu-net.ru
N. I. Pirogov Russian State Medical University, Moscow
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