New potentialities in symptom-modifying therapy of osteoarthrosis


如何引用文章

全文:

详细

Aim. To examine efficacy and tolerance of the drug Bora-Bora in patients with osteoarthrosis.
Material and methods. Bora-Bora and nimesulid were given to 20 patients with a verified diagnosis of osteoarthrosis (OA). 20 control patients received nimesulid alone. Treatment efficacy was evaluated by quantitative parameters of articular syndrome, indices of periarticular muscles affection estimated before the treatment, 2, 6 and 8 weeks after the start of the treatment. Ultrasonic investigation of the joints and periarticular tissues was conducted before and after the treatment course.
Results. The response to Bora-Bora was seen on day 10 of therapy. Bora-Bora attenuated pain syndrome in the joints and periarticular tissues, improved joint function more effectively than nimesulid (p < 0.05). Bora-Bora is a good anelgetic. It is well tolerated and can be recommended for OA treatment.

参考

  1. Насонова В. А., Фоломеева О. М., Амирджанова В. Н. и др. Болезни костно-мышечной системы и соединительной ткани в России: динамика статистических показателей за 5 лет (1994-1998). Науч.-практ. ревматол. 2000; 2: 4-12.
  2. Насонов Е. Л. Современные направления фармакотерапии остеоартроза. Consilium Medicum 2004; 3 (9): 408-415.
  3. Насонов Е. Л. Ревматология: мультидисплинарные проблемы. В кн.: Материалы научно-практической конф. "Новое в диагностике и лечении ревматических заболеваний". М.; 2002. 4-9.
  4. Маколкин В. И., Меньшикова И. В. Остеоартроз коленного сустава: современный подход к проблеме лечения. Тер. арх. 2005; 77 (5): 83-86.
  5. Бадокин В. В. Медикаментозная терапия первичного (идиопатического) остеоартроза. Рус. мед. журн. 2003; 11 (5): 243-245.
  6. Nielsen F. H., Hunt C. D., Mullen L. M. et al. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J. 1987; 1: 394-397.
  7. Nzietchueng R. M., Dousset В., Frank P. et al. Mechanisms implicated in the effects of boron on wound healing. J. Trace Elem. Med. Biol. 2002; 16: 239-244.
  8. Rico H., Crespo E., Hernandes E. R. et al. Influence of boron supplementation on vertebral and femoral bone mass in rats on strenuous treadmill exercise. A morphometric, densitometric and histomorphometric study. J. Clin. Densitom. 2002; 5: 187-192.
  9. Travers R. L., Rennie G. C., Newnham R. E. Boron and arthritis: the result of a double-blind pilotstudy. J. Nutr. Med. 1990; 1: 81-85.

补充文件

附件文件
动作
1. JATS XML
下载

版权所有 © Consilium Medicum, 2009

Creative Commons License
此作品已接受知识共享署名-非商业性使用-相同方式共享 4.0国际许可协议的许可。
 

Address of the Editorial Office:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Correspondence address:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Managing Editor:

  • Tel.: +7 (926) 905-41-26
  • E-mail: e.gorbacheva@ter-arkhiv.ru

 

 © 2018-2021 "Consilium Medicum" Publishing house


##common.cookie##