电邮这篇文章 Amiodarone (cordarone) efficiency in atrial extrasystoles
- 作者: Reingardene DI1, Azaravichene AP1
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- 期: 卷 79, 编号 6 (2004)
- 页面: 87-89
- 栏目: Editorial
- ##submission.dateSubmitted##: 09.04.2020
- ##submission.datePublished##: 15.06.2004
- URL: https://ter-arkhiv.ru/0040-3660/article/view/29864
- ID: 29864
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Aim. To assess antiarrhythmic amiodarone efficacy of suppressing atrial extrasystoles resistant to other antiarrhythmic modalities.
Material and methods. The antiarrhythmic effect of amiodarone was studied in 70 patients (38 males, 32 females, mean age 49.6 ± 1.7 years, mean duration of arrhythmia 4.9 ± 1,5 years). The loading oral dose of amiodarone was 600-1200 mg/day for 10 days, mean maintenance dose - 1656.25 mg a weak, mean duration of treatment - 27.5 ± 3.2 months. The response to amiodarone was estimated by repeated 24-h Holter monitoring.
Results. A complete response was observed in 78.5% patients in loading and in 65.7% patients in maintenance therapy. A partial antiarrhythmic response was seen in 8.57 and 16.41% patients, respectively.
Conclusion. Amiodarone is a basic drug against ventricular arrhythmia. Its effectiveness in suppression of atrial extrasystole is weaker but also appropriate.
Material and methods. The antiarrhythmic effect of amiodarone was studied in 70 patients (38 males, 32 females, mean age 49.6 ± 1.7 years, mean duration of arrhythmia 4.9 ± 1,5 years). The loading oral dose of amiodarone was 600-1200 mg/day for 10 days, mean maintenance dose - 1656.25 mg a weak, mean duration of treatment - 27.5 ± 3.2 months. The response to amiodarone was estimated by repeated 24-h Holter monitoring.
Results. A complete response was observed in 78.5% patients in loading and in 65.7% patients in maintenance therapy. A partial antiarrhythmic response was seen in 8.57 and 16.41% patients, respectively.
Conclusion. Amiodarone is a basic drug against ventricular arrhythmia. Its effectiveness in suppression of atrial extrasystole is weaker but also appropriate.
参考
- Brendorp В., Pedersen О., Torp-Pedersen С. et al. A benefitrisk assessment of class III antiarrhythmic agents. Drug Saf. 2002; 25 (12): 847-865.
- Singh B. N. Amiodarone: the expanding antiarrhythmic role and how to follow a patient on chronic therapy. Clin. Cardiol. 1997; 20 (7): 608-618.
- Auer J., Berent R., Eber B. Amiodarone in the prevention and treatment of arrhythmia. Curr. Opin. Invest. Drugs 2002; 3 (7): 1037-1044.
- Le Heuzey J. Y. The best in 2000 on arrhythmia. Arch. Mai. Coeur2001; 94 (1): 21-26.
- Chaudhry G. M., Haffajee С. I. Antiarrhythmic agents and proarrhythmia. Crit. Care Med. 2002; 28 (10): 158-164.
- Singh B. N. Significance and control of cardiac arrhythmias in patients with congestive cardiac failure. Heart Fail. Rev. 2002; 7 (3): 285-300.
- Chow Т., Galvin J., McGovern B. Antiarrhythmic drug therapy in patients with renal failure, liver failure, and congestive heart failure. Heart Dis. 1999; 1 (2): 98-107.
- Faber T. S., Zehender M. Antiarrhythmic therapy in patients with heart failure. Ther. Umsch. 2000; 57 (5): 324-332.
- Auricchio A., Klein M. Arrhythmias in heart failure. Curr. Treat. Options Cardiovasc. Med. 2000; 2 (4): 329-339.
- Goldschlager N., Epstein A. E., Naccarelli G. et al. Practical guidelines for clinicians who treat patients with amiodarone. Practice Guidelines Subcommittee, North American Society of Pacing and Electrophysiology. Arch. Intern. Med. 2000; 160 (12): 1741-1748.
- Chung M. K. Cardiac surgery: postoperative arrhythmias. Crit. Care Med. 2000; 28 (10): 136-144.
- Lee K. L., Toi Y. T. Long-term low-dose amiodarone therapy in the management of ventricular and supraventricular tachyarrhythmias: efficacy and safety. Clin. Cardiol. 1997; 20 (40): 372-377.
- Hebbar A. K., Hueston W. J. Management of common arrhythmias: part I. Supraventricular arrhythmias. Am. Fam. Physician 2002; 65 (12): 2479-2486.
- Rho R. W., Bridges С. R., Kocovic D. Management of postoperative arrhythmias. Semin. Thorac. Cardiovasc. Surg. 2000: 12 (4): 349-361.
- Stevenson W. G., Ellison K. E., Sweeney M. O. et al. Management of arrhythmias in heart failure. Cardiol. Rev. 2002; 10 (1): 8-11.
- Hammami S., Djilani-Horchani H., Smati B. et al. Immediate postoperative arrhythmias following pneumonectomy for lung cancer. Tunis Med. 2001; 79 (11): 617-620.
- Wirth K. J., Knobloch K. Differential effects of dofetilide, amiodarone, and class Ic drugs on left and right atrial refractoriness and left atrial vulnerability in pigs. Naunyn-Schmiedeberg'sArch. Pharmacol. 2001; 363: 166-174.
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