Arterial stiffness as a predictor of cardiovascular events in coronary heart disease


Cite item

Full Text

Abstract

To date, there is much evidence confirming that impaired arterial elastic properties have a direct impact on prognosis in patients with chronic renal failure, arterial hypertension, or diabetes mellitus in the general population and in the elderly. At the same time, in most cohort studies the manifestations of coronary heart disease (CHD) constitute about two thirds of developed cardiovascular events (CVE); the value of arterial stiffness after CHD manifestations has not been conclusively ascertained. There are various opinions on the mechanism and pattern of this association. Rigidity of large vessels may be a marker of cardiac artery lesion, on the one hand, and promote deterioration of myocardial ischemia in the presence of coronary atherosclerosis, on the other. This review of literature discusses the pathogenetic and clinical aspects of the impact of stiffness of the great vessels on the development of CVE.

About the authors

Yana Arturovna Orlova

Email: orlova@cardio.ru

Fail' Taipovich Ageev

Email: ageev@cardio.ru

Ya A Orlova

Russian Cardiology Research-and-Industrial Complex, Russian Agency for Medical Technologies

Russian Cardiology Research-and-Industrial Complex, Russian Agency for Medical Technologies

F T Ageyev

Russian Cardiology Research-and-Industrial Complex, Russian Agency for Medical Technologies

Russian Cardiology Research-and-Industrial Complex, Russian Agency for Medical Technologies

References

  1. Grundy S. M., Balady G. J., Criqui M. H. et al. Primary prevention of coronary head disease: guidance from Framingham: a statement for healthcare professionals from the American Heart Association's Task Force on Risk Reduction. Circulation 1998; 97: 1876-1887.
  2. Conroy R. M., Pyorala K., Fitzgerald A. P. et al. On behalf of the SCORE project group. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur. Heart J. 2003; 24: 987-1003.
  3. Grundy S. M., Pasternak R., Greenland P. et al. Assessment of cardiovascular risk by use of multiple-risk-factor assessment equations. Circulation 1999; 100: 1481-1492.
  4. Smith S. C. Jr., Blair S. N., Criqui M. H. et al. and Secondary Prevention Panel. Preventing heart attack and death in patients with coronary disease. Circulation 1995; 92: 2-4.
  5. Pocock S. J., McCormack V., Gueyffier F. et al. A score for predicting risk of death from cardiovascular disease in adults with raised blood pressure, based on individual patient data from randomised controlled trials. Br. Med. J. 2001; 323: 75-81.
  6. Clayton T. C., Lubsen J., Pocock S. et al. Risk score for predicting death, myocardial infarction, and stroke in patients with stable angina, based on a large randomised trial cohort of patients. Br. Med. J. 2005; 331: 869.
  7. Marchioli R., Avanzini F., Barzi F. et al. Assessment of absolute risk of death after myocardial infarction by use of multiple-risk-factor assessment equations: GISSI-Prevenzione mortality risk chart. Eur. Heart J. 2001; 22(22): 2085-2103.
  8. Arnett D. K., Evans G. W., Riley W. A. Arterial stiffness: a new cardiovascular risk factor? Am. J. Epidemiol. 1994; 140: 669- 682.
  9. Woo K. S., Chook P., Lolin Y. I. et al. Hyperhomocyst(e)inemia is a risk factor for arterial endothelial disfunction in humans. Circulation 1997; 96: 2542-2544.
  10. Salomaa V., Roley W., Kark J. D. et al. Non-insulin-dependent diabetes mellitus and fasting glucose and insulin concentrations are associated with arterial stiffness indexes. The ARIC Study. Circulation 1995; 91: 1432-1443.
  11. Czernichow S., Bertrais S., Oppert J. M. et al. Body composition and fat repartition in relation to structure and function of large arteries in middle-aged adults (the SU. VI. MAX study). Int. J. Obes. Relat. Metab. Disord. 2005: 29(7): 826-832.
  12. Nagano A., Nakamura R., Sato S. et al. Association between serum C-reactive protein levels and pulse wave velocity: a population-based cross-sectional study in a general population. Atherosclerosis 2005: 180(1): 189-195.
  13. Wilkinson I. B., Qasem A., McEniery C. M. et al. Nitric oxide regulates local arterial distensibility in vivo. Circulation 2002; 105: 213-.
  14. Blacher J., Guerin A. P., Pannier B. et al. Impact of aortic stiffness on survival in end-stage renal disease. Circulation 1999; 99: 2434-2439.
  15. Guerin A. P., Blacher J., Pannier B. et al. Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure. Circulation 2001: 103(7): 987-992.
  16. Posadzy-Malaczynska A., Kosch M., Hausberg M. et al. Arterial distensibility, intima media thickness and pulse wave velocity after renal transplantation and in dialysis normotensive patients. Int. Angiol. 2005; 24(1): 89-94.
  17. London G. M. Cardiovascular disease in chronic renal failure: pathophysiologic aspects. Semin. Dial. 2003; 16(2): 85-94.
  18. Laurent S., Boutouyrie P., Asmar R. et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 2001; 37: 1236-1241.
  19. Verdecchia P., Schillaci G., Borgioni C. et al. Ambulatory pulse pressure a potent predictor of total cardiovascular risk in hypertension. Hypertension 1998; 32: 983-988.
  20. de Simone G., Roman M. J., Koren M. J. et al. Stroke volume/ pulse pressure ratio and cardiovascular risk in arterial hypertension. Hypertension 1999; 33: 800-805.
  21. Cruickshank K., Riste L., Anderson S. G. et al. Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function? Circulation 2002; 106: 2085-2090.
  22. Stamler J., Vaccaro O., Neaton J. D. et al. Diabetes, other risk factors, and 12 year cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial (MRFIT). Diabet. Care 1993; 16: 434-444.
  23. Woolam G., Schnur P., Vallbona C. et al. The pulse wave velocity as an early indicator of atherosclerosis in diabetic subjects. Circulation 1962; 25: 533-539.
  24. Scarpello J. H., Martin T. R., Ward J. D. Ultrasound measurements of pulse-wave velocity in the peripheral arteries of diabetic subjects. Clin. Sci. 1980; 58: 53-57.
  25. Hansen T. W., Staessen J. A., Torp-Pedersen C. et al. Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population. Circulation 2006; 113: 664- 670.
  26. Meaume S., Rudnichi A., Lynch A. et al. Aortic pulse wave velocity as a marker of cardiovascular disease in subjects over 70 years old. J. Hypertens. 2001; 19(5): 871-877.
  27. Nakashima T., Tanikawa J. A study of human aortic distensibility with relation to atherosclerosis and aging. Angiology 1971; 22: 477-490.
  28. Avolio A. P., Deng F. Q., Li W. Q. et al. Effects of aging on arterial distensibility in populations with high and low prevalence of hypertension: comparison between urban and rural communities in China. Circulation 1985; 71: 202-210.
  29. Riley W. A., Evans G. W., Sharrett A. R. et al. Variation of common carotid artery elasticity with intimal-medial thickness: the ARIC Study: Atherosclerosis Risk in Communities. Ultrasound Med. Biol. 1997; 23: 157-164.
  30. Sato H., Hayashi J., Harashima K. et al. A population-based study of arterial stiffness index in relation to cardiovascular risk factors. J. Atheroscler. Thromb. 2005; 12(3): 175-180.
  31. Shokawa T., Imazu M., Yamamoto H. et al. Pulse wave velocity predicts cardiovascular mortality: findings from the Hawaii-Los Angeles-Hiroshima study. Circ. J. 2005; 69(3): 259-264.
  32. Boutouyrie P., Tropeano A. I., Asmar R. et al. Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study. Hypertension 2002; 39: 10-15.
  33. Sutton-Tyrrell K., Najjar S. S., Boudreau R. M. et al. Health ABC Study. Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in wellfunctioning older adults. Circulation 2005; 111: 3384-3390.
  34. Shoji T., Emoto M., Shinohara K. et al. Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease. J. Am. Soc. Nephrol. 2001; 12: 2117-2124.
  35. Guidelines for the management of arterial hypertension. The task force for the management of arterial hypertension of ESH and of ESC. J. Hypertens. 2007; 25(6): 1105-1187.
  36. van Popele N. M., Grobbee D. E., Bots M. L. et al. Association between arterial stiffness and atherosclerosis. The Rotterdam Study. Stroke 2001; 32: 454.
  37. Schwartzkopff B., Motz W., Frenzel H. et al. Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension. Circulation 1993; 88: 993-1003.
  38. Isnard R. N., Pannier B. M., Laurent S. et al. Pulsatile diameter and elastic modulus of the aortic arch in essential hypertension: a noninvasive study. J. Am. Coll. Cardiol. 1989; 13: 399-405.
  39. Roman M. J., Saba P. S., Pini R. et al. Parallel cardiac and vascular adaptation in hypertension. Circulation 1992; 86: 1909-1918.
  40. Laurent S., Boutouyrie P., Lacolley P. Structural and genetic bases of arterial stiffness. Hypertension 2005; 45: 1050-1055.
  41. Laurent S., Cockcroft J., Van Bortel L. et al. On behalf of European Network for Non-invasive investigation of Large Arteries. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur. Heart J. 2006; 27: 2588-2605.
  42. Farrar D. J., Bond M. G., Sawyer J. K. et al. Pulse wave velocity and morphological changes associated with early atherosclerosis progression in the aortas of cynomolgus monkeys. Cardiovasc. Res. 1984; 47(3): 425-432.
  43. Farrar D. J., Bond M. G., Riley W. A., Sawyer J. K. Anatomic correlates of aortic pulse wave velocity and carotid artery elasticity during atherosclerosis progression and regression in monkeys. Circulation 1991; 83: 1754-1763.
  44. London G. M. Cardiovascular disease in chronic renal failure: pathophysiologic aspects. Semin. Dial. 2003; 16(2): 85-94.
  45. Safar M. E., London G. M. The arterial system in human hypertension. In: Swales J. D., ed. Textbook of hypertension. London: Blackwell Scientific; 1994. 85-102.
  46. O'Rourke M. E. Mechanical principles in arterial disease. Hypertension 1995; 26: 2-9.
  47. Kelly R. P., Tunin R., Kass D. A. Effect of reduced aortic compliance on cardiac efficiency and contractile function of in situ canine left ventricle. Circ. Res. 1992; 71 (3): 490-502.
  48. Chang K. C., Tseng Y. Z., Kuo T. S., Chen H. I. Impaired left ventricular relaxation and arterial stiffness in patients with essential hypertension. Clin. Sci. 1994; 87: 641-647.
  49. Asmar R. G., Pannier B., Santoni J. Ph. et al. Reversion of cardiac hypertrophy and reduced arterial compliance after converting enzyme inhibition in essential hypertension. Circulation 1988; 78: 941-950.
  50. London G. M., Pannier B., Guerin A. P. et al. Cardiac hypertrophy, aortic compliance, peripheral resistance, and wave reflection in end-stage renal disease. Comparative effects of ACE inhibition and calcium channel blockade. Circulation 1994; 90: 2786-2796.
  51. Boutouyrie P., Laurent S., Girerd X. et al. Common carotid artery distensibility and patterns of left ventricular hypertrophy in hypertensive patients. Hypertension 1995; 25: 651-659.
  52. Watanabe H., Obtsuka S., Kakibana M., Ugisbita Y. Coronary circulation in dogs with an experimental decrease in aortic compliance. J. Am. Coll. Cardiol. 1993; 21: 1497-1506.
  53. Kingwell B. A., Waddell T. K., Medley T. L. et al. Large artery stiffness predicts ischemic threshold in patients with coronary artery disease. J. Am. Coll. Cardiol. 2002; 40(4): 773-779.
  54. Hirai T., Sasayama S., Kawasaki T., Yagi S. Stiffness of systemic arteries in patients with myocardial infarction: a noninvasive method to predict severity of coronary atherosclerosis. Circulation 1989; 80: 78-86.
  55. Covic A., Haydar A. A., Bhamra-Ariza P. et al. Aortic pulse wave velocity and arterial wave reflections predict the extent and severity of coronary artery disease in chronic kidney disease patients. J. Nephrol. 2005; 18(4): 388-396.
  56. Tsushima M. Noninvasive quantitative assessment of atherosclerosis with the pulse wave velocity (PWV) and the computed tomography of the abdominal aorta. Nippon Rinsho 2002; 60(5): 933-940.
  57. Ouchi Y., Terashita K., Nakamura T. et al. Aortic pulse wave velocity in patients with coronary atherosclerosis-a comparison with coronary angiographic findings. Nippon Ronen Igakkai Zasshi 1991; 28(1): 40-54.
  58. Imanish R., Seto S., Toda G. et al. High brachial-ankle pulse wave velocity is an independent predictor of the presence of coronary artery disease in men. Hypertens. 2004; 2: 71-78.
  59. Илюхин О. В., Калганова Е. Л., Илюхина М. В., Лопатин Ю. М. Скорость распространения пульсовой волны у больных коронарным атеросклерозом. Кардиология 2005; 6: 42-.
  60. McLeod A. L., Uren N. G., Wilkinson I. B. et al. Non-invasive measures of pulse wave velocity correlate with coronary arterial plaque load in humans. J. Hypertens. 2004; 22(2): 363-368.
  61. Fukuda D., Yoshiyama M., Shimada K. et al. Relation between aortic stiffness and coronary flow reserve in patients with coronary artery disease. Heart 2006; 92(6): 759-762.
  62. Nakashima T., Tanikawa J. A study of human aortic distensibility with relation to atherosclerosis and aging. Angiology 1971; 22: 477-490.
  63. Avolio A. P., Deng F. Q., Li W. Q. et al. Effects of aging on arterial distensibility in populations with high and low prevalence of hypertension: comparison between urban and rural communities in China. Circulation 1985; 71: 202-210.
  64. Eliakim M., Sapoznikov D., Weinman J. Pulse wave velocity in healthy subjects and in patients with various disease states. Am. Heart J. 1971; 82(4): 448-457.
  65. Megnien J. L., Simon A., Denarie N. et al. Aortic stiffening does not predict coronary and extracoronary atherosclerosis in asymptomatic men at risk for cardiovascular disease. Am. J. Hypertens. 1998; 11(1): 293-301.
  66. van Popele N. M., Mattace-Raso F. U., Vliegenthart R. et al. Aortic stiffness is associated with atherosclerosis of the coronary arteries in older adults: the Rotterdam Study. J. Hypertens. 2006; 24(12): 2347-2348.
  67. Dijk J. M., Algra A., van der Graaf Y. et al. SMART study group. Carotid stiffness and the risk of new vascular events in patients with manifest cardiovascular disease. The SMART study. Eur. Heart J. 2005; 26(12): 1213-1220.
  68. Tomiyama H., Koij Y., Yambe M. et al. Brachial-ankle pulse wave velocity is a simple and independent predictor of prognosis in patients with acute coronary syndrome. Circ. J. 2005; 69: 815-822.
  69. Stefanadis C., Dernellis J., Tsiamis E. et al. Aortic stiffness as a risk factor for recurrent acute coronary events in patients with ischaemic heart disease. Eur. Heart J. 2001; 22(2): 181.
  70. Mattace-Raso F. U. S., van der Cammen T. J. M., Hofman A. et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation 2006; 113: 657-663.
  71. Chirinos J. A., Zambrano J. P., Chakko S. et al. Aortic pressure augmentation predicts adverse cardiovascular events in patients with established coronary artery disease. Hypertension 2005; 45: 980-.
  72. Weber T., Auer J., O'Rourke M. F. et al. Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions. Eur. Heart J. 2005; 26(24): 2657-2663.
  73. Kulio I. J., Malik A. R. Arterial ultrasonography and tonometry as adjuncts to cardiovascular risk stratification. J. Am. Coll. Cardiol. 2007; 49(13): 1413-1426.
  74. Bergel D. H. Cardiovascular fluid dynamics. London: Academic Press; 1972; vol. 1.
  75. Williams B., Lacy P. S., Thom S. M. et al. CAFE Investigators; Angio-Scandinavian Cardiac Outcomes Trial Investigators; CAFE Steering Committee Writing Committee. Differential impact of blood pressure lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study. Circulation 2006; 1l3: 1213-1225.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2010 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
 

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Alabyan Street, 13/1, Moscow, 127055, Russian Federation

Managing Editor:

  • Tel.: +7 (926) 905-41-26
  • E-mail: e.gorbacheva@ter-arkhiv.ru

 

 © 2018-2021 "Consilium Medicum" Publishing house


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies