Сахарный диабет и центральная нервная система
- Авторы: Суркова ЕВ1
-
Учреждения:
- Эндокринологический научный центр Минздрава России
- Выпуск: Том 88, № 10 (2016)
- Страницы: 82-86
- Раздел: Передовая статья
- Статья получена: 11.04.2020
- Статья опубликована: 15.10.2016
- URL: https://ter-arkhiv.ru/0040-3660/article/view/32649
- DOI: https://doi.org/10.17116/terarkh201688682-86
- ID: 32649
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Аннотация
Аннотация В обзоре рассматриваются современные представления о состоянии центральной нервной системы (ЦНС) при сахарном диабете (СД). Обсуждается отношение к термину «диабетическая энцефалопатия». Рассматриваются данные исследований когнитивных функций при СД 1-го и 2-го типов, а также результаты визуализации мозговых структур, полученные с использованием современных технологий. Приводятся результаты изучения факторов, индуцирующих изменения мозга при СД и связанных с ними когнитивных расстройств. Представлены доказательства более весомого влияния на указанные процессы гипергликемии по сравнению с гипогликемией, перечислены другие возможные факторы воздействия помимо контроля уровня глюкозы в крови. Изложены современные взгляды на функции инсулина в ЦНС и связь центральной инсулинорезистентности с болезнью Альцгеймера. Приведены актуальные данные по применению интраназального инсулина, которое носит пока исследовательский характер, но, как позволяют судить полученные результаты, может в будущем явиться перспективным методом лечения и профилактики снижения когнитивных функций как у больных СД, так и лиц без СД.
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